Sánchez-Villalobos José Manuel, Villegas-Martínez Irene, Pérez-Vicente José Antonio
Epilepsy Unit, Department of Neurology, Santa Lucía University Hospital, Cartagena, Spain. Address correspondence and reprint requests to Irene Villegas Martínez, MD, PhD, Hospital Universitario Santa Lucía, Calle Mezquita sn, Paraje Los Arcos, 30202, Cartagena, Murcia, Spain; E-mail:
Clin Neuropharmacol. 2018 Mar/Apr;41(2):80-81. doi: 10.1097/WNF.0000000000000267.
Antiepileptic drugs have been known to worsen myasthenia gravis (MG) symptoms, and therefore, in patients who suffer both conditions (myasthenia and epilepsy), treatment selection is difficult. We report 2 cases of patients with MG who were safely treated with lacosamide. Evidence about antiepileptic drug treatment and adverse effects in MG is reviewed.
已知抗癫痫药物会加重重症肌无力（MG）的症状，因此，对于同时患有这两种疾病（重症肌无力和癫痫）的患者，治疗方案的选择很困难。我们报告了2例使用拉科酰胺安全治疗的重症肌无力患者。本文回顾了有关重症肌无力抗癫痫药物治疗及不良反应的证据。
