一名葡萄糖-6-磷酸脱氢酶缺乏症患者的细小病毒B19相关噬血细胞性淋巴组织细胞增生症
Parvovirus B19-associated Hemophagocytic Lymphohistiocytosis in a Patient With Glucose-6-phosphate Dehydrogenase Deficiency.
作者信息
Zečkanović Aida, Perovnik Matej, Jazbec Janez, Petrovec Miroslav, Pokorn Marko, Kavčič Marko
机构信息
Faculty of Medicine, University of Ljubljana.
Department for Pediatric Hematology and Oncology, University Children's Hospital of Ljubljana.
出版信息
J Pediatr Hematol Oncol. 2018 Nov;40(8):e550-e552. doi: 10.1097/MPH.0000000000001109.
We report a case of a 12-year-old male with glucose-6-phosphate dehydrogenase deficiency presenting with clinical signs of sepsis and pancytopenia. Investigations revealed parvovirus B19 (PVB19)-associated hemophagocytic lymphohistiocytosis (HLH). The patient recovered fully and quickly with symptomatic treatment. Current evidence suggests that PVB19-associated HLH has a favorable prognosis. Mild undiagnosed cases of HLH may be the cause of pancytopenia in PVB19 infections.
我们报告一例12岁男性，患有葡萄糖-6-磷酸脱氢酶缺乏症，出现败血症和全血细胞减少的临床症状。检查发现为细小病毒B19（PVB19）相关的噬血细胞性淋巴组织细胞增生症（HLH）。该患者经对症治疗后迅速完全康复。目前的证据表明，PVB19相关的HLH预后良好。HLH的轻度未诊断病例可能是PVB19感染中全血细胞减少的原因。
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