Zečkanović Aida, Perovnik Matej, Jazbec Janez, Petrovec Miroslav, Pokorn Marko, Kavčič Marko
Faculty of Medicine, University of Ljubljana.
Department for Pediatric Hematology and Oncology, University Children's Hospital of Ljubljana.
J Pediatr Hematol Oncol. 2018 Nov;40(8):e550-e552. doi: 10.1097/MPH.0000000000001109.
We report a case of a 12-year-old male with glucose-6-phosphate dehydrogenase deficiency presenting with clinical signs of sepsis and pancytopenia. Investigations revealed parvovirus B19 (PVB19)-associated hemophagocytic lymphohistiocytosis (HLH). The patient recovered fully and quickly with symptomatic treatment. Current evidence suggests that PVB19-associated HLH has a favorable prognosis. Mild undiagnosed cases of HLH may be the cause of pancytopenia in PVB19 infections.
我们报告一例12岁男性，患有葡萄糖-6-磷酸脱氢酶缺乏症，出现败血症和全血细胞减少的临床症状。检查发现为细小病毒B19（PVB19）相关的噬血细胞性淋巴组织细胞增生症（HLH）。该患者经对症治疗后迅速完全康复。目前的证据表明，PVB19相关的HLH预后良好。HLH的轻度未诊断病例可能是PVB19感染中全血细胞减少的原因。
