Bal Amanjit, Mishra Baijayantimala, Singh Navneet, Das Ashim, Jindal S K
Departments of Histopathology, Virology and Pulmonary Medicine, PGIMER, Chandigarh, India.
APMIS. 2009 Oct;117(10):773-7. doi: 10.1111/j.1600-0463.2009.02528.x.
Myocarditis is a common cardiac disease that is identified on routine postmortem examinations. Initially, coxsackie viruses, other enteroviruses and adenoviruses were thought to be more common causes of myocarditis; however, recently, parvovirus B19 (PVB19) as well as human herpesvirus 6 (HHV6) have entered the arena. We describe autopsy findings of a patient who had a lethal myocarditis with haemophagocytic lympho-histiocytosis in a course of systemic PVB19 infection. The present case illustrates the unusually severe and rapid course of PVB19 myocarditis with associated haemophagocytic lympho-histiocytosis leading to death.
心肌炎是一种常见的心脏疾病，在常规尸检中可被发现。最初，柯萨奇病毒、其他肠道病毒和腺病毒被认为是心肌炎更常见的病因；然而，最近细小病毒B19（PVB19）以及人类疱疹病毒6型（HHV6）也成为了病因。我们描述了一名在全身性PVB19感染过程中发生致命性心肌炎并伴有噬血细胞性淋巴组织细胞增生症患者的尸检结果。本病例说明了PVB19心肌炎伴有相关噬血细胞性淋巴组织细胞增生症时异常严重且迅速的病程，最终导致死亡。
