Neurosciences Research Center, Department of Psychiatry, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Department of Psychiatry, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Asian J Psychiatr. 2018 Jan;31:63-66. doi: 10.1016/j.ajp.2018.01.003. Epub 2018 Feb 2.
Women likely attempt suicide more than men and sex hormones or menstrual cycle may be associated with female suicide attempts. There are debates regarding the correlation of premenstrual dysphoric disorder (PMDD) and suicidal behaviors. The objective of this study was to examine if PMDD was associated with suicidal attempts as sex hormones are contributed in its pathogenesis.
As a case-control study 120 fertile woman with regular menstrual cycles attempting suicide and admitted to a general hospital were compared with a matched control group of 120 women selected among those accompanying other patients in other wards. Psychiatric interview based on DSM-5 criteria was conducted for diagnosing PMDD.
There was a significantly higher frequency of PMDD in suicide attempters than in the controls (P = 0.001); while no remarkable difference was seen in frequency of premenstrual syndrome (PMS) between the two groups (P = 0.294) and attempting suicide was not related to the menstrual cycle (P = 0.52).
This study suggests that PMDD may be associated with suicidal attempts, however it is not related to menstrual cycle. No relationship was found between PMS and suicidal acts.
女性自杀的可能性高于男性，而性激素或月经周期可能与女性自杀企图有关。关于经前期烦躁障碍（PMDD）和自杀行为之间的相关性存在争议。本研究的目的是检验 PMDD 是否与自杀企图有关，因为性激素参与了其发病机制。
作为一项病例对照研究，我们比较了 120 名有规律月经周期且试图自杀的生育期女性和因其他疾病在其他病房陪同其他患者的 120 名女性对照组。采用基于 DSM-5 标准的精神科访谈来诊断 PMDD。
自杀者中 PMDD 的频率明显高于对照组（P=0.001）；而两组之间经前期综合征（PMS）的频率无显著差异（P=0.294），自杀与月经周期无关（P=0.52）。
本研究表明，PMDD 可能与自杀企图有关，但与月经周期无关。PMS 与自杀行为之间没有关系。
