Goel Atul, Jain Sonal, Shah Abhidha
Department of Neurosurgery, King Edward Memorial Hospital and Seth G.S. Medical College, Mumbai, India; Department of Neurosurgery, Lilavati Hospital and Research Centre, Mumbai, India.
Department of Neurosurgery, King Edward Memorial Hospital and Seth G.S. Medical College, Mumbai, India.
World Neurosurg. 2018 Feb;110:533-543. doi: 10.1016/j.wneu.2017.07.007.
To evaluate the musculoskeletal and soft tissue neural alterations in cases with group A basilar invagination.
Between January 2007 and August 2016, 510 patients with group A basilar invagination were surgically treated. The radiologic images of these patients were reviewed retrospectively. The patients were divided into 4 groups: group A1, comprising 60 patients with syringomyelia; group A2, comprising 354 patients with "external syrinx," marked by excessive cerebrospinal fluid (CSF) in the extramedullary space; group A3, comprising 51 patients with both syringomyelia and external syrinx; and group A4, comprising 45 patients with no abnormality of CSF cavitation in the spinal canal.
A number of musculoskeletal and neural parameters, including the extent of basilar invagination, degree of angulation of the odontoid process, and facet malalignment, were evaluated in each of the 4 groups. The degree of basilar invagination was 6-27.4 mm (average, 15.85 mm) in group A1, 4.3-24.5 mm (average, 12.56 mm) in group A2, 5.6-17.6 mm (average 10.8 mm) in group A3, and 5.2-17.3 mm (average, 11.74 mm) in group A4. The angle of inclination of the odontoid process was 61.1-90.7 degrees (average, 71.4 degrees) in group A1, 30.5-79.8 degrees (average, 60.05 degrees) in group A2, 68.5-78.3 degrees (average, 73.4 degrees) in group A3, and 62.2-87.4 degrees (average, 71.2 degrees) in group A4.
The nature of bone malformations directly influences the presence or absence of external syrinx and syringomyelia.
评估甲型基底凹陷症患者的肌肉骨骼和软组织神经改变。
2007年1月至2016年8月期间，对510例甲型基底凹陷症患者进行了手术治疗。对这些患者的放射影像进行回顾性分析。患者被分为4组：A1组，包括60例患有脊髓空洞症的患者；A2组，包括354例有“外部空洞”的患者，其特征为髓外间隙脑脊液（CSF）过多；A3组，包括51例同时患有脊髓空洞症和外部空洞的患者；A4组，包括45例椎管内脑脊液空洞无异常的患者。
对4组患者中的每一组都评估了一些肌肉骨骼和神经参数，包括基底凹陷的程度、齿状突的成角程度和小关节排列不齐情况。A1组基底凹陷程度为6 - 27.4毫米（平均15.85毫米），A2组为4.3 - 24.5毫米（平均12.56毫米），A3组为5.6 - 17.6毫米（平均10.8毫米），A4组为5.2 - 17.3毫米（平均11.74毫米）。A1组齿状突倾斜角度为61.1 - 90.7度（平均71.4度），A2组为30.5 - 79.8度（平均60.05度），A3组为68.5 - 78.3度（平均73.4度），A4组为62.2 - 87.4度（平均71.2度）。
骨畸形的性质直接影响外部空洞和脊髓空洞症的有无。
