Division of Respiratory and Critical Care Physiology and Medicine, Harbor-UCLA Medical Center, 1000 West Carson Street, Box #402, Torrance, CA 90502, USA.
Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine and University Hospital, 12631 East 17th Avenue, M/S C323, Office #8102, Aurora, CO 80045, USA.
Clin Chest Med. 2018 Mar;39(1):245-259. doi: 10.1016/j.ccm.2017.11.014.
Current advances in guided bronchoscopy methods permit minimally invasive access to essentially any area of the lungs. This provides a potential means to treat patients with localized lung malignancies who might not otherwise tolerate conventional treatment, which commonly relies on surgical resection. Ablation methods have long been used for bronchoscopic treatment of central airway malignancies and percutaneous treatment of peripheral lung cancer. This article reviews ablation technologies being adapted for use with guided bronchoscopy and the current state of investigation for the treatment of peripheral lung malignancies.
目前,支气管镜引导方法的进展使得微创进入肺部的任何区域成为可能。这为那些可能无法耐受常规治疗(通常依赖于手术切除)的局限性肺部恶性肿瘤患者提供了一种潜在的治疗方法。消融方法长期以来一直用于支气管镜治疗中央气道恶性肿瘤和经皮治疗周围型肺癌。本文综述了用于支气管镜引导下治疗的消融技术以及目前针对周围型肺癌治疗的研究现状。