决奈达隆起始治疗后出现急性肝细胞性黄疸：一例报告
Acute Hepatocellular Jaundice After Dofetilide Initiation: A Case Report.
作者信息
Rose Patrick Gary, Seabury Robert, Cwikla Gregory
机构信息
State University of New York Upstate Medical University, Syracuse, NY, USA.
出版信息
Hosp Pharm. 2018 Feb;53(1):55-58. doi: 10.1177/0018578717738079. Epub 2017 Nov 3.
Abstract
Dofetilide's hepatotoxicity is not well described. In this case report, we describe acute hepatocellular jaundice related to dofetilide use in a 33-year-old male being treated for atrial fibrillation. Both viral and ischemic causes of hepatocellular damage were ruled out as unlikely in this case. This case report outlines a rare yet probable report of idiosyncratic dofetilide-induced liver injury.
摘要
决奈达隆的肝毒性尚未得到充分描述。在本病例报告中，我们描述了一名33岁正在接受房颤治疗的男性因使用决奈达隆而出现的急性肝细胞性黄疸。在该病例中，肝细胞损伤的病毒和缺血性病因均被排除，可能性不大。本病例报告概述了一例罕见但可能由决奈达隆引起的特异质性肝损伤报告。
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