Waage Siri, Pallesen Ståle, Moen Bente Elisabeth, Bjorvatn Bjørn
Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Norwegian Competence Center for Sleep Disorders, Haukeland University Hospital, Bergen, Norway.
Front Neurol. 2018 Jan 29;9:21. doi: 10.3389/fneur.2018.00021. eCollection 2018.
Insomnia and excessive sleepiness are among the most commonly reported sleep problems related to shift work. Sleep-related movement disorders have, however, received far less attention in relation to such work schedules. The objective of this study was to investigate the association between different shift work schedules and the prevalence of Restless legs syndrome/Willis-Ekbom disease (RLS/WED) in a large sample of Norwegian nurses. Our hypothesis was that shift working nurses would report higher prevalence of RLS/WED compared to day workers. A total of 1,788 nurses with different work schedules (day work, two-shift rotation, night work, three shift rotation) participated in a cohort study, started in 2008/2009. Four questions about RLS/WED based on the diagnostic criteria were included in wave 4 (2012). RLS/WED prevalence rates across different shift schedules were explored by the Pearson chi-square test. Logistic regression analysis was used to assess the association between RLS/WED and work schedules and shift work disorder (SWD) with adjustment for sex, age, marital status, smoking, and caffeine use. In total, 90.0% of the nurses were females, mean age 36.5 years (SD = 8.6, range 25-67). The overall prevalence of RLS/WED was 26.8%. We found no significant differences between the prevalence of RLS/WED across the different shift schedules, ranging from 23.3% (day work) to 29.4% (night work). There was a significant difference ( < 0.001) in the prevalence of RLS/WED between nurses having SWD (33.5%) compared to nurses not having SWD (23.8%). SWD remained significantly associated with RLS/WED in the adjusted logistic regression analysis (1.56, CI: 1.24-1.97). This study did not support the hypothesis. RLS/WED was associated with SWD, which might indicate that nurses vulnerable to shift work also are sensitive to other complaints related to a misalignment of the biological clock.
失眠和过度嗜睡是与轮班工作相关的最常见的睡眠问题。然而,与这种工作时间表相关的睡眠相关运动障碍受到的关注要少得多。本研究的目的是调查挪威大量护士样本中不同轮班工作时间表与不安腿综合征/Willis-Ekbom病(RLS/WED)患病率之间的关联。我们的假设是,与日班工作人员相比,轮班工作的护士报告的RLS/WED患病率更高。共有1788名具有不同工作时间表(日班、两班轮换、夜班、三班轮换)的护士参与了一项始于2008/2009年的队列研究。第4波(2012年)纳入了基于诊断标准的4个关于RLS/WED的问题。通过Pearson卡方检验探讨不同轮班时间表的RLS/WED患病率。采用逻辑回归分析评估RLS/WED与工作时间表及轮班工作障碍(SWD)之间的关联,并对性别、年龄、婚姻状况、吸烟和咖啡因使用情况进行校正。总体而言,90.0%的护士为女性,平均年龄36.5岁(标准差=8.6,范围25-67岁)。RLS/WED的总体患病率为26.8%。我们发现不同轮班时间表的RLS/WED患病率之间无显著差异,范围从23.3%(日班)到29.4%(夜班)。与没有SWD的护士(23.8%)相比,有SWD的护士(33.5%)的RLS/WED患病率存在显著差异(<0.001)。在调整后的逻辑回归分析中,SWD与RLS/WED仍显著相关(1.56,置信区间:1.24-1.97)。本研究不支持该假设。RLS/WED与SWD相关,这可能表明易患轮班工作的护士对与生物钟失调相关的其他不适也很敏感。