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制造与操作分子机器:一项多学科挑战。

Making and Operating Molecular Machines: A Multidisciplinary Challenge.

作者信息

Baroncini Massimo, Casimiro Lorenzo, de Vet Christiaan, Groppi Jessica, Silvi Serena, Credi Alberto

机构信息

CLAN-Center for Light Activated Nanostructures Università di Bologna and Consiglio Nazionale delle Ricerche Via Gobetti 101 40129 Bologna Italy.

Dipartimento di Scienze e Tecnologie Agro-alimentari Università di Bologna Viale Fanin 50 40127 Bologna Italy.

出版信息

ChemistryOpen. 2018 Feb 2;7(2):169-179. doi: 10.1002/open.201700181. eCollection 2018 Feb.

DOI:10.1002/open.201700181
PMID:29435402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5795756/
Abstract

Movement is one of the central attributes of life, and a key feature in many technological processes. While artificial motion is typically provided by macroscopic engines powered by internal combustion or electrical energy, movement in living organisms is produced by machines and motors of molecular size that typically exploit the energy of chemical fuels at ambient temperature to generate forces and ultimately execute functions. The progress in several areas of chemistry, together with an improved understanding of biomolecular machines, has led to the development of a large variety of wholly synthetic molecular machines. These systems have the potential to bring about radical innovations in several areas of technology and medicine. In this Minireview, we discuss, with the help of a few examples, the multidisciplinary aspects of research on artificial molecular machines and highlight its translational character.

摘要

运动是生命的核心属性之一,也是许多技术过程的关键特征。虽然人工运动通常由以内燃或电能为动力的宏观发动机提供,但生物体中的运动是由分子大小的机器和马达产生的,这些机器和马达通常利用环境温度下化学燃料的能量来产生力并最终执行功能。化学多个领域的进展,以及对生物分子机器的更深入理解,导致了各种各样完全合成的分子机器的发展。这些系统有可能在技术和医学的几个领域带来根本性的创新。在这篇迷你综述中,我们借助几个例子讨论人工分子机器研究的多学科方面,并突出其转化特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/94abac870082/OPEN-7-169-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/94abac870082/OPEN-7-169-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/4f4b5647615b/OPEN-7-169-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/64d66ac930ef/OPEN-7-169-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/914c891bec00/OPEN-7-169-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/0aeeb198c8cd/OPEN-7-169-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/1b46ef4b3554/OPEN-7-169-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/f69674f8c837/OPEN-7-169-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/55d89ed35814/OPEN-7-169-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/09f94d3c20b1/OPEN-7-169-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/11a127455f5b/OPEN-7-169-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/369eaaf93a42/OPEN-7-169-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d7c/5795756/94abac870082/OPEN-7-169-g013.jpg

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