Department of Internal Medicine, Office F4069 Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Curr HIV/AIDS Rep. 2018 Apr;15(2):120-126. doi: 10.1007/s11904-018-0381-4.
As access to effective antiretroviral therapy (ART) expands globally, a decline in AIDS-related morbidity and mortality has been complicated by rising rates of noncommunicable diseases (NCDs). This review provides a brief description of NCDs and existing gaps on knowledge about NCDs among HIV-infected adults mostly in Africa.
Recent reports show that one in every five persons living with HIV has a chronic illness, predominantly diabetes and/or hypertension, depression, and most of these conditions are either not diagnosed or not being managed. Human papilloma virus-associated anal dysplasia occurs among 70% of HIV-infected women in RLS. Recognizing risk factors for NCDs and providing effective screening and optimal care remains challenging. Research is urgently needed to carefully characterize HIV-associated NCDs in RLS. Such studies should provide a framework for high-priority NCDs that the limited resources can be focused on in these settings.
目的综述:随着有效的抗逆转录病毒疗法(ART)在全球范围内的普及,艾滋病相关发病率和死亡率的下降因非传染性疾病(NCDs)发病率的上升而变得复杂。本综述简要描述了非传染性疾病,并介绍了非洲地区 HIV 感染者对 NCDs 相关知识的现有差距。
最近发现:最近的报告显示,每五名 HIV 感染者中就有一人患有慢性疾病,主要是糖尿病和/或高血压、抑郁症,其中大多数疾病要么未被诊断,要么未得到治疗。在 RLS 中,70%的 HIV 感染女性患有人乳头瘤病毒相关的肛门发育不良。认识 NCDs 的风险因素并提供有效的筛查和最佳护理仍然具有挑战性。迫切需要研究来仔细描述 RLS 中与 HIV 相关的 NCDs。这些研究应为这些环境中有限资源可集中关注的高优先级 NCDs 提供框架。