Ringelstein E B, Zeumer H, Brückmann H, Stübben G, Sturm K W
Fortschr Neurol Psychiatr. 1986 Jul;54(7):216-31. doi: 10.1055/s-2007-1001868.
Percutaneous transluminal angioplasty (PTA) is a semiinvasive, non-operative transvascular technique for dilatation of stenosed vessel segments by help of balloon catheters. This technique was applied to 30 out of 42 patients with a subclavian steal mechanism due to highgrade proximal subclavian artery (PSA) lesions. The transfemoral, transaxillary or both approaches were used. A staging of the severity of the subclavian steal mechanism on the basis of the pre-interventional Doppler ultrasound findings (Grade I-IV) was proposed for adequate selection of patients for angioplasty. During balloon dilatation of the subclavian artery permanent CW Doppler monitoring of the ipsilateral vertebral blood flow velocity was performed at the mastoid. Balloon dilatation failed to be effective in 4 patients with complete subclavian artery occlusions (Stage IV). In 26 patients with high-grade stenoses of the proximal subclavian artery (Stage II/III), angioplasty led to recanalisation of the vessel and abolishment of the steal mechanism. However, relief or improvement of the concomitant subclavian steal syndrome could not be achieved except in one-third or two-thirds of the patients, respectively. Long term follow-up with repeat Doppler sonography indicated a complete removal of the subclavian lesions in 50% of the cases, whereas the remaining patients produced some kind of re-stenosis. However, repeat angioplasty became necessary in only 5 cases and was permanently successful in two of them. If patients with complete subclavian artery occlusions were excluded, the complication rate due to angioplasty was very low. Embolism into the finger arteries could only be observed once. In another case, accidental dissection and complete occlusion of the distal subclavia artery occurred but underwent spontaneous recanalisation. Doppler monitoring of vertebral flow velocity was very useful for both control of the effectiveness of the dilatation procedure and deeper insight into the pathophysiology of the subclavian steal mechanism. An unexpected delay phenomenon concerning the re-establishment of cephalad vertebral flow direction was observed immediately after recanalisation of the subclavian artery and was thought to protect the posterior circulation against early embolism due to mobilisation of plaque debris within the proximal subclavian segment. From an angiological point of view, the outcome of percutaneous transluminal angioplasty does not yet meet the success rates of various modern extra-thoracic surgical procedures for operative treatment of subclavian steal mechanism. However, the rate of improvement of clinical signs and symptoms is equal with both methods.(ABSTRACT TRUNCATED AT 400 WORDS)
经皮腔内血管成形术(PTA)是一种借助球囊导管扩张狭窄血管段的半侵入性非手术血管技术。该技术应用于42例因锁骨下动脉近端(PSA)高度病变导致锁骨下窃血机制的患者中的30例。采用经股动脉、经腋动脉或两种途径联合。基于介入前多普勒超声检查结果(I-IV级)对锁骨下窃血机制的严重程度进行分期,以适当选择血管成形术患者。在球囊扩张锁骨下动脉期间,在乳突处对同侧椎动脉血流速度进行连续波多普勒监测。对于4例锁骨下动脉完全闭塞(IV期)的患者,球囊扩张无效。在26例近端锁骨下动脉高度狭窄(II/III期)的患者中,血管成形术使血管再通并消除了窃血机制。然而,除了分别有三分之一或三分之二的患者外,伴随的锁骨下窃血综合征未能得到缓解或改善。重复多普勒超声的长期随访显示,50%的病例锁骨下病变完全消除,而其余患者出现某种再狭窄。然而,仅5例患者需要再次血管成形术,其中2例永久成功。如果排除锁骨下动脉完全闭塞的患者,血管成形术的并发症发生率非常低。仅观察到1次手指动脉栓塞。在另一例中,意外发生远端锁骨下动脉夹层和完全闭塞,但随后自发再通。椎动脉血流速度的多普勒监测对于控制扩张手术的有效性以及更深入了解锁骨下窃血机制的病理生理学非常有用。在锁骨下动脉再通后立即观察到关于头端椎动脉血流方向重新建立的意外延迟现象,认为这可保护后循环免受近端锁骨下节段内斑块碎片移动导致的早期栓塞。从血管病学角度来看,经皮腔内血管成形术的结果尚未达到各种现代胸外手术治疗锁骨下窃血机制的成功率。然而,两种方法在临床体征和症状改善率方面相当。(摘要截选至400字)