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腭咽功能障碍的手术治疗:干预措施与结果的系统评价

Surgery for Velopharyngeal Dysfunction: A Systematic Review of Interventions and Outcomes.

作者信息

de Blacam Catherine, Smith Susan, Orr David

机构信息

1 Department of Plastic and Reconstructive Surgery, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland.

2 Department of General Practice, Royal College of Surgeons in Ireland, Dublin, Ireland.

出版信息

Cleft Palate Craniofac J. 2018 Mar;55(3):405-422. doi: 10.1177/1055665617735102. Epub 2017 Dec 14.

Abstract

OBJECTIVE

This systematic review sought to evaluate the consensus in the literature regarding the surgical management of VPD and to determine whether a particular procedure results in superior speech outcome or less morbidity Design: A systematic review was carried out according to PRISMA-P guidelines. Systematic review software was used to facilitate 3-stage screening and data extraction by 2 reviewers.

SETTING

University teaching hospital.

PATIENTS, PARTICIPANTS: Studies that reported perceptual speech assessment or obstructive sleep apnea (OSA) in patients who had undergone surgery for VPD were included in the review.

INTERVENTIONS

Four categories of surgery for VPD were examined-pharyngeal flap, sphincter pharyngoplasty, palatoplasty, and posterior pharyngeal wall augmentation.

MAIN OUTCOME MEASURES

Perceptual speech assessment, need for further surgery, and occurrence of OSA were the outcomes of interest.

RESULTS

Eighty-three relevant studies were identified, comprising data on 4011 patients. Pharyngeal flap was the most common procedure (64% of patients). Overall, 70.7% of patients attained normal resonance and 65.3% attained normal nasal emission. There was no notable difference in speech outcomes, need for further surgery, or occurrence of OSA across the 4 categories of surgery examined. Heterogeneous groups of patients were reported upon and a variety of perceptual speech assessment scales were used.

CONCLUSIONS

There is a lack of consensus in the literature to guide procedure selection for patients with VPD. The development of a standardized minimum data set to record postoperative speech, OSA, and patient-reported outcomes is required.

摘要

目的

本系统评价旨在评估文献中关于腭咽闭合不全(VPD)手术治疗的共识,并确定特定手术是否能带来更好的语音效果或更低的发病率。设计:根据PRISMA-P指南进行系统评价。使用系统评价软件协助两名评审员进行三阶段筛选和数据提取。

设置

大学教学医院。

患者、参与者:纳入的研究报告了接受VPD手术患者的感知语音评估或阻塞性睡眠呼吸暂停(OSA)情况。

干预措施

检查了四类VPD手术——咽瓣手术、括约肌咽成形术、腭成形术和咽后壁增厚术。

主要观察指标

感兴趣的结果包括感知语音评估、进一步手术的需求和OSA的发生情况。

结果

共识别出83项相关研究,包含4011例患者的数据。咽瓣手术是最常见的手术方式(占患者的64%)。总体而言,70.7%的患者实现了正常共鸣,65.3%的患者实现了正常鼻漏气。在所检查的四类手术中,语音效果、进一步手术的需求或OSA的发生情况没有显著差异。报告的患者群体存在异质性,并且使用了多种感知语音评估量表。

结论

文献中缺乏指导VPD患者手术选择的共识。需要制定一个标准化的最小数据集来记录术后语音、OSA和患者报告的结果。

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