Hopkins M, Valberg B M, Robinson L M
J Neurosci Nurs. 1986 Aug;18(4):211-3. doi: 10.1097/01376517-198608000-00012.
In 1967 the first extracranial to intracranial (EC/IC) arterial anastomosis was performed. Since that time, EC/IC bypass surgery has become a widely accepted surgical treatment for patients with intracranial stenotic or occlusive atherosclerotic lesions. In 1977 an international multicenter randomized trial was established to determine whether EC/IC bypass surgery reduced the rate of stroke and stroke-related death in patients with recent hemispheric and/or retinal ischemic symptoms. Completed and analyzed in 1985, the International Cooperative Study of Extracranial/Intracranial Arterial Anastomosis of 1,377 patients provides an evaluation of the surgical procedure for stroke prevention. This paper will discuss the study's objectives and organization, the methods employed, the trial results, and implications.
1967年进行了首例颅外至颅内（EC/IC）动脉吻合术。自那时起，EC/IC搭桥手术已成为颅内狭窄或闭塞性动脉粥样硬化病变患者广泛接受的外科治疗方法。1977年开展了一项国际多中心随机试验，以确定EC/IC搭桥手术是否能降低近期出现半球和/或视网膜缺血症状患者的中风发生率及与中风相关的死亡率。1985年完成并分析的1377例患者的颅外/颅内动脉吻合术国际合作研究，对预防中风的手术方法进行了评估。本文将讨论该研究的目的和组织、采用的方法、试验结果及意义。
