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20 年随访研究比较高水平运动员前交叉韧带撕裂的手术与非手术治疗。

Twenty-Year Follow-up Study Comparing Operative Versus Nonoperative Treatment of Anterior Cruciate Ligament Ruptures in High-Level Athletes.

机构信息

Department of Orthopaedic Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.

Department of General Practice, Erasmus University Medical Center, Rotterdam, the Netherlands.

出版信息

Am J Sports Med. 2018 Apr;46(5):1129-1136. doi: 10.1177/0363546517751683. Epub 2018 Feb 13.

Abstract

BACKGROUND

An anterior cruciate ligament (ACL) rupture has major consequences at midterm follow-up, with an increasing chance of developing an old knee in a young patient. The long-term (≥20 years) effects of the operative and nonoperative treatment of ACL ruptures are still unclear.

PURPOSE

To compare the long-term treatment outcomes of operative versus nonoperative treatment of ACL ruptures in high-level athletes.

STUDY DESIGN

Cohort study; Level of evidence, 2.

METHODS

Fifty patients with an ACL rupture were eligible for participation, and they were treated either nonoperatively (n = 25) in 1992, consisting of structured rehabilitation and lifestyle adjustments, or operatively (n = 25) between 1994 and 1996 with an arthroscopic transtibial bone-patellar tendon-bone technique. The patients in the nonoperative group were drawn from those who responded well to 3 months of nonoperative treatment, whereas the patients in the operative group were drawn from those who had persistent instability after 3 months of nonoperative treatment. Both groups were pair-matched and assessed at 10- and 20-year follow-up regarding radiological knee osteoarthritis, functional outcomes (Lysholm, International Knee Documentation Committee [IKDC], Tegner, Knee injury and Osteoarthritis Outcome Score), meniscal status, and knee stability (KT-1000 arthrometer, pivot-shift test, Lachman test, 1-legged hop test).

RESULTS

All 50 patients (100%) were included in the current study for follow-up. After 20 years, we found knee osteoarthritis in 80% of the operative group compared with 68% of the nonoperative group ( P = .508). There was no difference between groups regarding functional outcomes and meniscectomy performed. The median IKDC subjective score was 81.6 (interquartile range [IQR], 59.8-89.1) for the operative group and 78.2 (IQR, 61.5-92.0) for the nonoperative group ( P = .679). Regarding the IKDC objective score, 21 patients (84%) in the operative group had a normal or near normal score (A and B) compared with 5 patients (20%) in the nonoperative group ( P < .001). The pivot-shift test finding was negative in 17 patients (68%) versus 3 patients (13%) for the operative and nonoperative groups, respectively ( P < .001), and the Lachman test finding was negative in 12 patients (48%) versus 1 patient (4%), respectively ( P = .002).

CONCLUSION

In this retrospective pair-matched follow-up study, we found that after 20-year follow-up, there was no difference in knee osteoarthritis between operative versus nonoperative treatment when treatment was allocated on the basis of a patient's response to 3 months of nonoperative treatment. Although knee stability was better in the operative group, it did not result in better subjective and objective functional outcomes.

摘要

背景

前交叉韧带(ACL)断裂在中期随访时有重大后果,年轻患者发生陈旧性膝关节的几率增加。ACL 断裂手术和非手术治疗的长期(≥20 年)效果仍不清楚。

目的

比较高水平运动员 ACL 断裂手术与非手术治疗的长期治疗结果。

研究设计

队列研究;证据等级,2 级。

方法

50 例 ACL 断裂患者符合参与条件,其中 25 例接受非手术治疗(1992 年),包括结构化康复和生活方式调整,25 例接受手术治疗(1994 年至 1996 年),采用关节镜下胫骨结节骨-髌腱-骨技术。非手术组的患者是从对 3 个月非手术治疗反应良好的患者中抽取的,而手术组的患者是从 3 个月非手术治疗后仍持续不稳定的患者中抽取的。两组均进行配对,并在 10 年和 20 年随访时评估放射学膝关节骨关节炎、功能结果(Lysholm、国际膝关节文献委员会 [IKDC]、Tegner、膝关节损伤和骨关节炎结果评分)、半月板状况和膝关节稳定性(KT-1000 关节测量仪、髌股关节试验、Lachman 试验、单腿跳跃试验)。

结果

当前研究共纳入 50 例(100%)患者进行随访。20 年后,我们发现手术组 80%的患者出现膝关节骨关节炎,而非手术组为 68%(P=.508)。两组在功能结果和半月板切除术方面无差异。手术组的 IKDC 主观评分中位数为 81.6(四分位距 [IQR],59.8-89.1),非手术组为 78.2(IQR,61.5-92.0)(P=.679)。关于 IKDC 客观评分,手术组有 21 例(84%)患者的评分正常或接近正常(A 和 B),而非手术组仅有 5 例(20%)(P<.001)。手术组髌股关节试验结果阴性的患者有 17 例(68%),而非手术组为 3 例(13%)(P<.001),Lachman 试验结果阴性的患者有 12 例(48%),而非手术组为 1 例(4%)(P=.002)。

结论

在这项回顾性配对随访研究中,我们发现,根据患者对 3 个月非手术治疗的反应进行治疗分配时,手术与非手术治疗在 20 年随访后膝关节骨关节炎方面无差异。虽然手术组的膝关节稳定性更好,但并没有导致更好的主观和客观功能结果。

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