• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

日本创伤患者的十年住院死亡率趋势:一项多中心观察性研究。

Ten-year inhospital mortality trends for patients with trauma in Japan: a multicentre observational study.

作者信息

Nagata Isao, Abe Toshikazu, Uchida Masatoshi, Saitoh Daizoh, Tamiya Nanako

机构信息

Department of Health Services Research, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

Graduate School of Comprehensive Human Sciences, Majors of Medical Sciences, University of Tsukuba, Tsukuba, Japan.

出版信息

BMJ Open. 2018 Feb 8;8(2):e018635. doi: 10.1136/bmjopen-2017-018635.

DOI:10.1136/bmjopen-2017-018635
PMID:29439071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5829856/
Abstract

OBJECTIVES

Trauma is one of the main causes of death in Japan, and treatments and prognoses of these injuries are constantly changing. We therefore aimed to investigate a 10-year trend (2004-2013) in inhospital mortality among patients with trauma in Japan.

DESIGN

Multicentre observational study.

SETTING

Japanese nationwide trauma registry (the Japan Trauma Data Bank) data.

PARTICIPANTS

All patients with trauma whose Injury Severity Score (ISS) were 3 and above, who were aged 15 years or older, and whose mechanisms of injury (MOI) were blunt and penetrating between 2004 and 2013 (n=90 833).

OUTCOME MEASURES

A 10-year trend in inhospital mortality.

RESULTS

Inhospital mortality for all patients with trauma significantly decreased over the study decade in our Cochran-Armitage test (P<0.001). Similarly, inhospital mortality for patients with ISS 16 or more and patients who scored 50% or better on the Trauma and Injury Severity Score (TRISS) probability of survival scale significantly decreased (P<0.001). In addition, the OR for inhospital mortality of these three patient groups decreased yearly after adjusting for age, gender, MOI, ISS, Glasgow Coma Scale, systolic blood pressure and respiratory rate on hospital arrival in multivariable logistic regression analyses. Furthermore, inhospital mortality for patient with blunt trauma significantly decreased in injury mechanism-stratified Mantel-extension testing (P<0.001). Finally, multivariable logistic regression analyses showed that the OR for inhospital mortality of patients with ISS 16 and over decreased each year after adding and adjusting for means of transportation and usage of whole-body CT.

CONCLUSION

Inhospital mortality for patients with trauma in Japan significantly decreased during the study decade after adjusting for patient characteristics, injury severity and the response environment after injury.

摘要

目的

创伤是日本主要的死亡原因之一,此类损伤的治疗方法和预后情况也在不断变化。因此,我们旨在调查日本创伤患者10年(2004 - 2013年)的院内死亡率趋势。

设计

多中心观察性研究。

设置

日本全国创伤登记处(日本创伤数据库)数据。

参与者

2004年至2013年期间所有损伤严重程度评分(ISS)为3及以上、年龄15岁及以上、损伤机制(MOI)为钝性和穿透性的创伤患者(n = 90833)。

观察指标

10年的院内死亡率趋势。

结果

在我们的 Cochr an - Armitage检验中,所有创伤患者的院内死亡率在研究的十年间显著下降(P < 0.001)。同样,ISS为16或更高的患者以及在创伤和损伤严重程度评分(TRISS)生存概率量表上得分50%或更高的患者的院内死亡率也显著下降(P < 0.001)。此外,在多变量逻辑回归分析中,在调整了年龄、性别、MOI、ISS、格拉斯哥昏迷量表、入院时收缩压和呼吸频率后,这三组患者的院内死亡率比值比逐年下降。此外,在损伤机制分层的Mantel - 扩展检验中,钝性创伤患者的院内死亡率显著下降(P < 0.001)。最后,多变量逻辑回归分析表明,在加入并调整了交通方式和全身CT使用情况后,ISS为16及以上患者的院内死亡率比值比逐年下降。

结论

在调整了患者特征、损伤严重程度和损伤后的反应环境后,日本创伤患者的院内死亡率在研究的十年间显著下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e42c/5829856/a7791520b4e1/bmjopen-2017-018635f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e42c/5829856/b68055f110ce/bmjopen-2017-018635f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e42c/5829856/a7791520b4e1/bmjopen-2017-018635f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e42c/5829856/b68055f110ce/bmjopen-2017-018635f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e42c/5829856/a7791520b4e1/bmjopen-2017-018635f02.jpg

相似文献

1
Ten-year inhospital mortality trends for patients with trauma in Japan: a multicentre observational study.日本创伤患者的十年住院死亡率趋势:一项多中心观察性研究。
BMJ Open. 2018 Feb 8;8(2):e018635. doi: 10.1136/bmjopen-2017-018635.
2
In-hospital trauma mortality has decreased in Japan possibly due to trauma education.日本的院内创伤死亡率可能因创伤教育而下降。
J Am Coll Surg. 2013 Nov;217(5):850-7.e1. doi: 10.1016/j.jamcollsurg.2013.05.026. Epub 2013 Aug 28.
3
Revised trauma scoring system to predict in-hospital mortality in the emergency department: Glasgow Coma Scale, Age, and Systolic Blood Pressure score.改良创伤评分系统预测急诊科住院病死率:格拉斯哥昏迷评分、年龄和收缩压评分。
Crit Care. 2011 Aug 10;15(4):R191. doi: 10.1186/cc10348.
4
Age-Related Characteristics and Outcomes for Patients With Severe Trauma: Analysis of Japan's Nationwide Trauma Registry.严重创伤患者的年龄相关特征和结局:日本全国创伤登记处的分析。
Ann Emerg Med. 2019 Mar;73(3):281-290. doi: 10.1016/j.annemergmed.2018.09.034. Epub 2018 Nov 15.
5
Is there an association between female gender and outcome in severe trauma? A multi-center analysis in the Netherlands.女性性别与严重创伤结局之间是否存在关联?荷兰多中心分析。
Scand J Trauma Resusc Emerg Med. 2019 Feb 13;27(1):16. doi: 10.1186/s13049-019-0589-3.
6
Exploring injury severity measures and in-hospital mortality: A multi-hospital study in Kenya.探索损伤严重程度指标与院内死亡率:肯尼亚的一项多医院研究。
Injury. 2017 Oct;48(10):2112-2118. doi: 10.1016/j.injury.2017.07.001. Epub 2017 Jul 8.
7
The impact of premorbid conditions on temporal pattern and location of adult blunt trauma hospital deaths.病前状况对成人钝性创伤医院死亡时间模式和地点的影响。
J Trauma. 2007 Jul;63(1):135-41. doi: 10.1097/TA.0b013e318068651d.
8
Is ventilator-associated pneumonia in trauma patients an epiphenomenon or a cause of death?创伤患者的呼吸机相关性肺炎是一种附带现象还是死亡原因?
Surg Infect (Larchmt). 2004 Fall;5(3):237-42. doi: 10.1089/sur.2004.5.237.
9
Has TRISS become an anachronism? A comparison of mortality between the National Trauma Data Bank and Major Trauma Outcome Study databases.TRISS 是否已经过时?国家创伤数据库与重大创伤结局研究数据库之间死亡率的比较。
J Trauma Acute Care Surg. 2012 Aug;73(2):326-31; discussion 331. doi: 10.1097/TA.0b013e31825a7758.
10
Systolic blood pressure below 110 mmHg is associated with increased mortality in penetrating major trauma patients: Multicentre cohort study.收缩压低于 110mmHg 与穿透性大创伤患者死亡率升高相关:多中心队列研究。
Resuscitation. 2012 Apr;83(4):476-81. doi: 10.1016/j.resuscitation.2011.10.018. Epub 2011 Nov 3.

引用本文的文献

1
Hospital volume-outcome relationship in emergency trunk interventional radiology for trauma patients: a nationwide observational study in Japan.创伤患者急诊躯干介入放射学中的医院容量-结局关系:日本的一项全国性观察性研究。
Eur Radiol. 2025 Jun 6. doi: 10.1007/s00330-025-11743-6.
2
Penetrating liver injury caused by a metal fragment from a blast accident in a factory: a case report.工厂爆炸事故中金属碎片导致的穿透性肝损伤:一例报告
J Trauma Inj. 2022 Aug;35(Suppl 1):S8-S14. doi: 10.20408/jti.2021.0085. Epub 2022 Jun 3.
3
Penetrating trauma on the rise- nine-year trends of severe trauma in Sweden.

本文引用的文献

1
Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma.严重创伤性出血患者的损伤控制复苏:来自东部创伤外科学会的实践管理指南
J Trauma Acute Care Surg. 2017 Mar;82(3):605-617. doi: 10.1097/TA.0000000000001333.
2
Mortality in Canadian Trauma Systems: A Multicenter Cohort Study.加拿大创伤系统中的死亡率:一项多中心队列研究。
Ann Surg. 2017 Jan;265(1):212-217. doi: 10.1097/SLA.0000000000001614.
3
Rural risk: Geographic disparities in trauma mortality.
穿透性创伤呈上升趋势——瑞典严重创伤的九年趋势
Eur J Trauma Emerg Surg. 2024 Dec;50(6):3189-3197. doi: 10.1007/s00068-024-02601-z. Epub 2024 Jul 30.
4
Incidence, demographics and outcomes of patients with penetrating injury: a Japanese nationwide 10-year retrospective study.穿透性损伤患者的发病率、人口统计学和结局:一项日本全国 10 年回顾性研究。
BMJ Open. 2023 Oct 28;13(10):e071873. doi: 10.1136/bmjopen-2023-071873.
5
In-Hospital Mortality Following Traumatic Injury in South Africa.南非创伤性损伤后的院内死亡率。
Ann Surg Open. 2022 Nov 9;3(4):e210. doi: 10.1097/AS9.0000000000000210. eCollection 2022 Dec.
6
Frequency of posttrauma complications during hospital admission and their association with Injury Severity Score.住院期间创伤后并发症的发生率及其与损伤严重程度评分的关系。
Clin Exp Emerg Med. 2023 Dec;10(4):410-417. doi: 10.15441/ceem.23.053. Epub 2023 Jul 13.
7
Evaluation of injury threshold from the number of rib fracture for predicting pulmonary injuries in blunt chest trauma.通过肋骨骨折数量评估损伤阈值以预测钝性胸部创伤中的肺损伤
Heliyon. 2023 Apr 6;9(4):e15278. doi: 10.1016/j.heliyon.2023.e15278. eCollection 2023 Apr.
8
China trauma treatment statistics 2019: A national retrospective study based on hospitalized cases.中国创伤治疗统计 2019:基于住院病例的全国回顾性研究。
Front Public Health. 2023 Feb 24;11:1116828. doi: 10.3389/fpubh.2023.1116828. eCollection 2023.
9
Evaluating the definition of severely injured patients: a Japanese nationwide 5-year retrospective study.评估重伤患者的定义:一项日本全国 5 年回顾性研究。
BMJ Open. 2023 Feb 23;13(2):e062619. doi: 10.1136/bmjopen-2022-062619.
10
Epidemiology, injury pattern and outcome of older trauma patients: A 15-year study of level-I trauma centers.老年创伤患者的流行病学、损伤模式和结局:15 年一级创伤中心研究。
PLoS One. 2023 Jan 30;18(1):e0280345. doi: 10.1371/journal.pone.0280345. eCollection 2023.
农村地区风险:创伤死亡率的地理差异
Surgery. 2016 Dec;160(6):1551-1559. doi: 10.1016/j.surg.2016.06.020. Epub 2016 Aug 6.
4
Immediate total-body CT scanning versus conventional imaging and selective CT scanning in patients with severe trauma (REACT-2): a randomised controlled trial.即刻全身 CT 扫描与常规成像和选择性 CT 扫描对严重创伤患者的比较(REACT-2):一项随机对照试验。
Lancet. 2016 Aug 13;388(10045):673-83. doi: 10.1016/S0140-6736(16)30932-1. Epub 2016 Jun 28.
5
Factors affecting mortality in older trauma patients-A systematic review and meta-analysis.影响老年创伤患者死亡率的因素——一项系统评价与荟萃分析
Injury. 2016 Jun;47(6):1170-83. doi: 10.1016/j.injury.2016.02.027. Epub 2016 Mar 16.
6
Evolution of patient outcomes over 14 years in a mature, inclusive Canadian trauma system.在一个成熟、包容性强的加拿大创伤系统中,患者14年的治疗结果演变情况。
World J Surg. 2015 Jun;39(6):1397-405. doi: 10.1007/s00268-015-2977-9.
7
Whole-body computed tomographic scanning leads to better survival as opposed to selective scanning in trauma patients: a systematic review and meta-analysis.与选择性扫描相比,全身计算机断层扫描可提高创伤患者的生存率:一项系统评价和荟萃分析。
J Trauma Acute Care Surg. 2014 Oct;77(4):534-9. doi: 10.1097/TA.0000000000000414.
8
Comparison of whole-body computed tomography vs selective radiological imaging on outcomes in major trauma patients: a meta-analysis.全身计算机断层扫描与选择性放射成像对严重创伤患者结局的比较:一项荟萃分析。
Scand J Trauma Resusc Emerg Med. 2014 Sep 2;22:54. doi: 10.1186/s13049-014-0054-2.
9
Association between helicopter with physician versus ground emergency medical services and survival of adults with major trauma in Japan.日本直升机搭载医生与地面紧急医疗服务运送重伤成年患者的生存率之间的关联。
Crit Care. 2014 Jul 9;18(4):R146. doi: 10.1186/cc13981.
10
The right treatment at the right time in the right place: a population-based, before-and-after study of outcomes associated with implementation of an all-inclusive trauma system in a large Canadian province.在适当的时间、适当的地点进行适当的治疗:一项基于人群的前后研究,评估在加拿大一个大省实施全覆盖创伤系统后相关结局的变化。
Ann Surg. 2015 Mar;261(3):558-64. doi: 10.1097/SLA.0000000000000745.