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用于肌肉骨骼疾病的传统中医推拿疗法:随机对照试验的系统评价和荟萃分析

Chuna (or Tuina) Manual Therapy for Musculoskeletal Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

作者信息

Lee Nam-Woo, Kim Gee-Heon, Heo In, Kim Koh-Woon, Ha In-Hyuk, Lee Jun-Hwan, Hwang Eui-Hyoung, Shin Byung-Cheul

机构信息

School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.

Korean Medicine Clinical Research Center, Korean Medicine Hospital, Pusan National University, Yangsan 50612, Republic of Korea.

出版信息

Evid Based Complement Alternat Med. 2017;2017:8218139. doi: 10.1155/2017/8218139. Epub 2017 Dec 26.

Abstract

OBJECTIVE

To review the literature and systematically evaluate the effectiveness of Chuna (or Tuina) manual therapy (C[T]MT) on pain and function for musculoskeletal disorders.

METHODS

We searched 15 English, Chinese, Japanese, and Korean databases using relevant keywords. All randomized controlled trials (RCTs) of C(T)MT for musculoskeletal disorders were considered, and we limited analyses to studies with a low-risk bias for randomization and/or allocation concealment.

RESULTS

Sixty-six RCTs with 6,170 participants were included. One sham-controlled RCT showed that C(T)MT relieved pain more effectively than a sham control (SMD -3.09 [-3.59, -2.59]). For active-controlled RCTs, pooled meta-analysis showed that C(T)MT had statistically significant effects on pain reduction, especially compared to traction ( < 0.00001), drugs ( = 0.04), and physical therapies ( < 0.0001). For functional improvement, combined effects of C(T)MT with drugs ( = 0.04) and traction ( = 0.05) also showed similar positive effects.

CONCLUSIONS

This systematic review suggests that C(T)MT is safe and effective for pain reduction and functional improvement for musculoskeletal diseases; however, the evidence for functional improvement was not as strong as for pain reduction. For future studies, high-quality RCTs such as sham-controlled studies with standardized interventions are needed to provide sufficient evidence on the effects of C(T)MT for musculoskeletal diseases. Protocol registration number is CRD42016038307 04/07/2016.

摘要

目的

回顾文献并系统评价传统中医推拿手法治疗(Chuna或Tuina手法治疗,C[T]MT)对肌肉骨骼疾病的疼痛及功能的有效性。

方法

我们使用相关关键词检索了15个英文、中文、日文和韩文数据库。纳入所有关于C(T)MT治疗肌肉骨骼疾病的随机对照试验(RCT),并将分析限于随机化和/或分配隐藏方面低偏倚风险的研究。

结果

纳入了66项RCT,共6170名参与者。一项假对照RCT显示,C(T)MT比假对照更有效地缓解疼痛(标准化均数差 -3.09 [-3.59, -2.59])。对于活性对照RCT,汇总Meta分析显示,C(T)MT在减轻疼痛方面具有统计学显著效果,尤其是与牵引(P<0.00001)、药物(P = 0.04)和物理治疗(P<0.0001)相比。对于功能改善,C(T)MT与药物(P = 0.04)和牵引(P = 0.05)联合使用也显示出类似的积极效果。

结论

本系统评价表明,C(T)MT对减轻肌肉骨骼疾病疼痛和改善功能是安全有效的;然而,功能改善方面证据的强度不如疼痛减轻方面。对于未来研究,需要高质量的RCT如采用标准化干预的假对照研究来提供关于C(T)MT对肌肉骨骼疾病疗效的充分证据。方案注册号为CRD42016038307 2016年7月4日。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47b7/5758860/89ef4842cd46/ECAM2017-8218139.001.jpg

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