Shu C X, Gong D, Zhang L P, Zhao J X
Suzhou Public Security Bureau, Suzhou 215131, China.
Institute of Forensic Science, Ministry of Public Security, Beijing 100038, China.
Fa Yi Xue Za Zhi. 2017 Dec;33(6):635-639. doi: 10.3969/j.issn.1004-5619.2017.06.014. Epub 2017 Dec 25.
As a new hypnotic, zopiclone is widely used in clinical treatment. There are many methods for determination of zopiclone, including spectrophotometry, chromatography and chromatography mass spectrum, etc. Present paper reviews different kinds of biological samples associated with zopiclone, extraction and purification methods, and determination and analysis methods, which aims to provide references for the relevant research and practice.
佐匹克隆作为一种新型催眠药，在临床治疗中被广泛应用。佐匹克隆的测定方法有很多种，包括分光光度法、色谱法以及色谱 - 质谱联用法等。本文综述了与佐匹克隆相关的各类生物样品、提取与净化方法以及测定与分析方法，旨在为相关研究与实践提供参考。
