头颈部癌症中的神经周围侵犯。
Perineural Invasion in Head and Neck Cancer.
机构信息
1 Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
2 Department of Pathology, Medical School, University of Michigan, Ann Arbor, MI, USA.
出版信息
J Dent Res. 2018 Jul;97(7):742-750. doi: 10.1177/0022034518756297. Epub 2018 Feb 14.
Abstract
Perineural invasion (PNI) is a mechanism of tumor dissemination that can provide a challenge to tumor eradication and that is correlated with poor survival. Squamous cell carcinoma, the most common type of head and neck cancer, has a high prevalence of PNI. This review provides an overview of clinical studies on the outcomes and factors associated with PNI in head and neck cancer and on findings on cancer-nerve crosstalk.
摘要
神经周围侵犯（PNI）是肿瘤扩散的一种机制，可能对肿瘤的清除造成挑战，并与不良预后相关。鳞状细胞癌是头颈部癌症中最常见的类型，其 PNI 的发生率较高。本文综述了头颈部癌症中与 PNI 相关的临床研究结果和影响因素，以及肿瘤-神经相互作用的研究结果。
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本文引用的文献
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