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生物可吸收光纤布拉格光栅

Bioresorbable optical fiber Bragg gratings.

作者信息

Pugliese Diego, Konstantaki Maria, Konidakis Ioannis, Ceci-Ginistrelli Edoardo, Boetti Nadia G, Milanese Daniel, Pissadakis Stavros

出版信息

Opt Lett. 2018 Feb 15;43(4):671-674. doi: 10.1364/OL.43.000671.

Abstract

We demonstrate, for the first time, an inscription and wet dissolution study of Bragg gratings in a bioresorbable calcium-phosphate glass optical fiber. Bragg gratings, with average refractive index changes of 5.8×10, were inscribed using 193 nm excimer laser radiation. Results on the dissolution of the irradiated fiber in simulated physiological conditions are presented after immersing a tilted Bragg grating in a phosphate buffered saline solution for 56 h; selective chemical etching effects are also reported. The investigations performed pave the way toward the use of such phosphate glass fiber Bragg gratings for the development of soluble photonic sensing probes for the efficient in vivo monitoring of vital mechanical or chemical parameters.

摘要

我们首次展示了对生物可吸收磷酸钙玻璃光纤中布拉格光栅的刻写和湿法溶解研究。使用193纳米准分子激光辐射刻写了平均折射率变化为5.8×10的布拉格光栅。将倾斜的布拉格光栅浸入磷酸盐缓冲盐溶液中56小时后,给出了辐照光纤在模拟生理条件下的溶解结果;还报告了选择性化学蚀刻效应。所进行的研究为使用这种磷酸盐玻璃光纤布拉格光栅开发可溶性光子传感探头以有效体内监测重要力学或化学参数铺平了道路。

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