与唑尼沙胺相关的史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症
Stevens-Johnson syndrome/toxic epidermal necrolysis associated with zonisamide.
作者信息
Vivar Karina L, Mancl Kimberly, Seminario-Vidal Lucia
机构信息
Department of Dermatology and Cutaneous Surgery University of South Florida Tampa Florida.
出版信息
Clin Case Rep. 2017 Dec 20;6(2):258-261. doi: 10.1002/ccr3.1288. eCollection 2018 Feb.
Abstract
This report highlights zonisamide as a potential cause of serious cutaneous reactions as well as its cross-reactivity with other sulfonamides. Here, we present a case of SJS-TEN due to zonisamide, which was effectively treated with IVIg. Subsequently, the patient was transitioned to levetiracetam for seizure control.
摘要
本报告强调了唑尼沙胺作为严重皮肤反应的潜在原因及其与其他磺胺类药物的交叉反应性。在此，我们报告一例因唑尼沙胺引起的史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症（SJS-TEN）病例，该病例通过静脉注射免疫球蛋白（IVIg）得到有效治疗。随后，患者改用左乙拉西坦控制癫痫发作。
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