与史蒂文斯-约翰逊综合征发病相关的高水平人疱疹病毒6型病毒血症：两例报告
High-level human herpesvirus-6 viremia associated with onset of Stevens-Johnson syndrome: report of two cases.
作者信息
Peppercorn Amanda F, Miller Melissa B, Fitzgerald David, Weber David J, Groben Pamela A, Cairns Bruce A
机构信息
Department of Medicine, University of North Carolina, School of Medicine, Chapel Hill, USA.
出版信息
J Burn Care Res. 2010 Mar-Apr;31(2):365-8. doi: 10.1097/BCR.0b013e3181d0f48b.
Abstract
The pathogenesis of Stevens-Johnson syndrome (SJS) remains obscure, but it has been associated with various infectious agents, including members of the herpesvirus family. We present the first report of high-level human herpesvirus-6 viremia at the onset of SJS, suggesting a possible new association. This finding supports the need for further investigation into the possible relationship between human herpesvirus-6 and SJS, which may illuminate the pathogenesis of SJS and bring us closer to achieving enhanced prevention and treatment of this rare disease.
摘要
史蒂文斯-约翰逊综合征（SJS）的发病机制仍不清楚，但它与多种感染因子有关，包括疱疹病毒科的成员。我们首次报告了SJS发病时出现的高水平人疱疹病毒6型病毒血症，提示可能存在一种新的关联。这一发现支持进一步研究人疱疹病毒6型与SJS之间可能的关系，这可能会阐明SJS的发病机制，并使我们更接近实现对这种罕见疾病的强化预防和治疗。
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