Kumar Rammohan, Natarajan Srikant, Sneha K S, Chitra Nunna Sai, Boaz Karen, Manaktala Nidhi
Oral and Maxillofacial Surgeon, TCR Multispeciality Hospital, Krishnagiri, Tamilnadu, India.
Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore, India.
Case Rep Dent. 2017;2017:5741821. doi: 10.1155/2017/5741821. Epub 2017 Dec 28.
The origin of a salivary gland tumour is attributed to cells at various levels of differentiation which present histologically as diverse tissues and cellular patterns. Mitochondria-rich, eosinophilic oncocytes are cells commonly encountered in salivary gland neoplasms. We report a case of mucoepidermoid carcinoma (MEC) in the palate of a 43-year-old female that exhibited a prominent oncocytic component. While the parotid and submandibular glands have been reported as predominant sites for oncocytic MEC (OMEC), the palate and minor salivary glands are rare sites for occurrence. Also, most of the reported cases of OMEC have been histologically of low-grade mucoepidermoid carcinoma with large cystic spaces and good prognosis. In this article, we discuss the differential diagnosis and diagnostic workup of an MEC presenting with oncocytes.
涎腺肿瘤的起源归因于不同分化水平的细胞，这些细胞在组织学上呈现为多样的组织和细胞模式。富含线粒体的嗜酸性嗜酸性细胞是涎腺肿瘤中常见的细胞。我们报告一例43岁女性腭部黏液表皮样癌（MEC），其具有显著的嗜酸性细胞成分。虽然腮腺和下颌下腺已被报道为嗜酸性细胞黏液表皮样癌（OMEC）的主要发生部位，但腭部和小涎腺是罕见的发生部位。此外，大多数报道的OMEC病例在组织学上为低级别黏液表皮样癌，具有大的囊腔且预后良好。在本文中，我们讨论了伴有嗜酸性细胞的MEC的鉴别诊断和诊断检查。
