Akhavan Setare, Aminimoghaddam Soheila, Rahmani Maryam
Department of Obstetrics and Gynecology, Medical School, Tehran University of Medical Sciences, Tehran, Iran.
Department of Obstetrics and Gynecology, Medical School, Iran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2017 Aug 31;31:50. doi: 10.14196/mjiri.31.50. eCollection 2017.
Cervical cancer is the second most common type of cancer among women. Effective screening programs can help cancer detection in early phases and reduce death. Metastasis to lymph nodes is one of the most prognostic factors in patients who underwent surgery. Also, a positive result from pathology report alert oncologist as a cause of death. Sentinel lymph node biopsy has been widely studied and clinically used for many types of cancer. Two techniques exist for detecting sentinel node in cervical cancer, which are Blue dye and gamma probe with radioactive isotope (99mTc). Moreover, lymphoscintigraphy has many advantages over the stain method. Detecting the sentinel node is performed via laparoscopy or laparotomy; former method is better and more accurate. Various researchers have focused on this method and its positive results; its superiority against full lymphadenectomy has been declared in previous studies. Moreover, the role of sentinel lymph nodes biopsy in cervical cancer is still being extensively studied. Sentinel lymph nodes (SLN) method has a higher accuracy level to detect metastasis. Hence, it can be considered as a more appropriate alternative for pelvic lymph node dissection (PLND), which is a standard technique. Altering the method to a standard clinical method needs in-depth researches and studies.
宫颈癌是女性中第二常见的癌症类型。有效的筛查项目有助于在早期阶段发现癌症并降低死亡率。淋巴结转移是接受手术治疗患者最重要的预后因素之一。此外,病理报告的阳性结果会提醒肿瘤学家这是一个死亡原因。前哨淋巴结活检已被广泛研究并临床应用于多种癌症类型。宫颈癌检测前哨淋巴结有两种技术,即蓝色染料法和使用放射性同位素(99mTc)的γ探针法。此外,淋巴闪烁造影术比染色法有许多优势。前哨淋巴结的检测通过腹腔镜或剖腹手术进行;前一种方法更好且更准确。许多研究人员都关注这种方法及其阳性结果;在先前的研究中已宣称其相对于根治性淋巴结清扫术的优越性。此外,前哨淋巴结活检在宫颈癌中的作用仍在广泛研究中。前哨淋巴结(SLN)方法在检测转移方面具有更高的准确性。因此,它可被视为盆腔淋巴结清扫术(PLND)这一标准技术的更合适替代方法。将该方法转变为标准临床方法需要深入的研究。