Sunnybrook Health Sciences, Toronto, Ontario, Canada.
Int J Gynecol Cancer. 2010 Oct;20(11 Suppl 2):S34-6. doi: 10.1111/IGC.0b013e3181f60d60.
Sentinel lymph node biopsy in cervical cancer is used to reduce the morbidity of a full lymph node dissection while improving the pickup rate of metastatic lymph nodes. The higher detection rate achieved can be explained by the following: the identification of the sentinel lymph node in an aberrant location which would not be routinely included in a systematic pelvic lymph node dissection, the sentinel lymph node is completely excised, and the routine use of ultrastaging. The higher detection rate achieved through sentinel lymph node biopsy can identify additional patients who could potentially benefit from adjuvant therapy therefore, in our view the gold standard of lymph node assessment in early stage cervical cancer has shifted and sentinel lymph node biopsy has taken the place of a complete lymphadenectomy.
宫颈癌前哨淋巴结活检用于降低全淋巴结清扫术的发病率，同时提高转移性淋巴结的检出率。更高的检出率可以通过以下几点来解释：识别异常位置的前哨淋巴结，这些淋巴结通常不会包含在系统盆腔淋巴结清扫术中；前哨淋巴结被完全切除；以及常规使用超分期。前哨淋巴结活检的更高检出率可以识别出更多可能受益于辅助治疗的患者，因此，在我们看来，早期宫颈癌淋巴结评估的金标准已经发生了变化，前哨淋巴结活检已经取代了完整的淋巴结清扫术。
