Yu Xiaoming, Cai He, Zheng Xingbang, Feng Junyan, Guan Jing
Reproductive Medicine Center, Peking University People's Hospital, Beijing, 100044, China.
Peking University International Hospital, Beijing, China.
Arch Gynecol Obstet. 2018 May;297(5):1169-1173. doi: 10.1007/s00404-018-4695-7. Epub 2018 Feb 14.
The study was carried out to clarify the IVF outcome after laparoscopic neosalpingostomy for infertile patients affected by hydrosalpinx stage III.
From January 2010 to June 2015, 91 subjects of hydrosalpinx stage III were treated in out center by laparoscopic surgery before IVF cycle. 43 underwent neosalpingostomy (group 1) and the remaining 48 underwent salpingestomy (group 2). We compared these patients and their IVF outcomes after two different surgical techniques.
There were no significant differences between the two groups, except a higher number of patients with bilaterial hydrosalpinges was noted in the neosalpingostomy group (79.1% vs. 56.3%, respectively). 25 patients with neosalpingostomy and 29 with salpingectomy achieved pregnancy by IVF. The ongoing pregnancy rate per cycle in group 1 and group 2 was 51.1 and 47.2%, respectively. Two cases of ampullary ectopic pregnancies were noted in group 1 and one case of right tube interstitial pregnancy in group 2. No significant difference was observed in live birth rate between the groups (48.9% vs. 45.3%, respectively).
The outcomes of IVF after neosalpingostomy were matchable with salpingectomy. For patients desire to preserve fallopian tubes, we recommend laparoscopic neosalpingostomy as an alternative choice to manage moderate hydrosalpinx before IVF.
本研究旨在阐明腹腔镜新输卵管造口术对Ⅲ期输卵管积水不孕患者体外受精(IVF)结局的影响。
2010年1月至2015年6月,91例Ⅲ期输卵管积水患者在体外受精周期前在本中心接受腹腔镜手术治疗。43例行新输卵管造口术(第1组),其余48例行输卵管切除术(第2组)。我们比较了这两组患者以及两种不同手术技术后的体外受精结局。
两组之间无显著差异,只是新输卵管造口术组双侧输卵管积水患者数量较多(分别为79.1%和56.3%)。25例行新输卵管造口术的患者和29例行输卵管切除术的患者通过体外受精成功妊娠。第1组和第2组每个周期的持续妊娠率分别为51.1%和47.2%。第1组发现2例壶腹部异位妊娠,第2组发现1例右侧输卵管间质部妊娠。两组的活产率无显著差异(分别为48.9%和45.3%)。
新输卵管造口术后的体外受精结局与输卵管切除术相当。对于希望保留输卵管的患者,我们建议在体外受精前,腹腔镜新输卵管造口术可作为治疗中度输卵管积水的一种替代选择。