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70岁以上患者的经皮腔内冠状动脉成形术

Percutaneous transluminal coronary angioplasty in patients over the age of 70 years.

作者信息

Dorros G, Janke L

出版信息

Cathet Cardiovasc Diagn. 1986;12(4):223-9. doi: 10.1002/ccd.1810120405.

DOI:10.1002/ccd.1810120405
PMID:2944593
Abstract

Percutaneous transluminal coronary angioplasty (PTCA) was attempted in 109 patients over the age of 70 years (mean age 75.9). The patients' clinical characteristics showed 55% with multivessel coronary disease, 86% with significant angina pectoris (Class II to IV), 16% with prior bypass surgery, and 2.7% with left ventricular dysfunction. Angioplasty data showed the mean percent diameter stenosis was reduced from 83 +/- 12% to 15 +/- 16%. One lesion was dilated in 67%, two lesions in 30%, and three lesions in 3% of the patients. A successful dilatation was achieved in 138/148 lesions (89%) with 90/109 patients (83%) clinically improved at hospital discharge. Significant complications were encountered in six patients (5.5%): three transmural infarctions (2.8%), two mortalities (1.8%), and one emergency surgical procedure (0.9%). Follow-up data (greater than or equal to 1 year) are available in 77 patients: 68 patients (92%) had an improved anginal status [49 patients (65%) had no angina]. During a mean follow-up of 23 +/- 10 months, there were two myocardial infarctions and three deaths. A clinically apparent recurrence occurred in 14 patients (17%). Repeat angioplasty was successfully performed in 13/14 patients. Bypass surgery was performed during the follow-up in three patients (two of whom had had a recurrence after a second successful angioplasty; one patient died during elective surgery). Transluminal coronary angioplasty can be performed in patients over age 70 with a good success rate, an acceptable complication rate, a relatively low clinically apparent recurrence rate, and should be considered as a therapeutic modality and alternative for the selected geriatric patient.

摘要

对109名70岁以上(平均年龄75.9岁)的患者尝试进行了经皮腔内冠状动脉成形术(PTCA)。患者的临床特征显示,55%患有多支冠状动脉疾病,86%有严重心绞痛(II至IV级),16%曾接受过搭桥手术,2.7%有左心室功能障碍。血管成形术数据显示,平均直径狭窄百分比从83±12%降至15±16%。67%的患者扩张了一处病变,30%的患者扩张了两处病变,3%的患者扩张了三处病变。148处病变中有138处(89%)成功扩张,109名患者中有90名(83%)在出院时临床症状改善。6名患者(5.5%)出现了严重并发症:3例透壁性心肌梗死(2.8%),2例死亡(1.8%),1例急诊手术(0.9%)。77名患者有随访数据(大于或等于1年):68名患者(92%)心绞痛症状改善[49名患者(65%)无心绞痛]。在平均23±10个月的随访期间,有2例心肌梗死和3例死亡。14名患者(17%)出现了临床明显的复发。14名患者中有13名成功进行了再次血管成形术。3名患者在随访期间接受了搭桥手术(其中2名患者在第二次成功血管成形术后复发;1名患者在择期手术期间死亡)。经皮腔内冠状动脉成形术可在70岁以上患者中进行,成功率高,并发症发生率可接受,临床明显复发率相对较低,应被视为选定老年患者的一种治疗方式和替代方法。

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Percutaneous transluminal coronary angioplasty in patients over the age of 70 years.70岁以上患者的经皮腔内冠状动脉成形术
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引用本文的文献

1
Initial and long-term results of coronary angioplasty and coronary bypass surgery in patients of 75 or older.75岁及以上患者冠状动脉成形术和冠状动脉搭桥手术的初始及长期结果
Br Heart J. 1993 Aug;70(2):122-5. doi: 10.1136/hrt.70.2.122.
2
Percutaneous transluminal coronary angioplasty in patients 70 years of age or older: 12 years' experience.70岁及以上患者的经皮腔内冠状动脉成形术:12年经验
Br Heart J. 1995 Sep;74(3):310-7. doi: 10.1136/hrt.74.3.310.
3
The treatment of coronary artery disease in the elderly.老年人冠状动脉疾病的治疗
Cardiovasc Drugs Ther. 1991 Apr;5(2):449-55. doi: 10.1007/BF03029769.
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Immediate and long term results of percutaneous coronary angioplasty in patients aged 70 and over.70岁及以上患者经皮冠状动脉腔内血管成形术的近期和远期结果
Br Heart J. 1992 Feb;67(2):138-43. doi: 10.1136/hrt.67.2.138.