Dorros G, Janke L
Cathet Cardiovasc Diagn. 1986;12(4):223-9. doi: 10.1002/ccd.1810120405.
Percutaneous transluminal coronary angioplasty (PTCA) was attempted in 109 patients over the age of 70 years (mean age 75.9). The patients' clinical characteristics showed 55% with multivessel coronary disease, 86% with significant angina pectoris (Class II to IV), 16% with prior bypass surgery, and 2.7% with left ventricular dysfunction. Angioplasty data showed the mean percent diameter stenosis was reduced from 83 +/- 12% to 15 +/- 16%. One lesion was dilated in 67%, two lesions in 30%, and three lesions in 3% of the patients. A successful dilatation was achieved in 138/148 lesions (89%) with 90/109 patients (83%) clinically improved at hospital discharge. Significant complications were encountered in six patients (5.5%): three transmural infarctions (2.8%), two mortalities (1.8%), and one emergency surgical procedure (0.9%). Follow-up data (greater than or equal to 1 year) are available in 77 patients: 68 patients (92%) had an improved anginal status [49 patients (65%) had no angina]. During a mean follow-up of 23 +/- 10 months, there were two myocardial infarctions and three deaths. A clinically apparent recurrence occurred in 14 patients (17%). Repeat angioplasty was successfully performed in 13/14 patients. Bypass surgery was performed during the follow-up in three patients (two of whom had had a recurrence after a second successful angioplasty; one patient died during elective surgery). Transluminal coronary angioplasty can be performed in patients over age 70 with a good success rate, an acceptable complication rate, a relatively low clinically apparent recurrence rate, and should be considered as a therapeutic modality and alternative for the selected geriatric patient.
对109名70岁以上(平均年龄75.9岁)的患者尝试进行了经皮腔内冠状动脉成形术(PTCA)。患者的临床特征显示,55%患有多支冠状动脉疾病,86%有严重心绞痛(II至IV级),16%曾接受过搭桥手术,2.7%有左心室功能障碍。血管成形术数据显示,平均直径狭窄百分比从83±12%降至15±16%。67%的患者扩张了一处病变,30%的患者扩张了两处病变,3%的患者扩张了三处病变。148处病变中有138处(89%)成功扩张,109名患者中有90名(83%)在出院时临床症状改善。6名患者(5.5%)出现了严重并发症:3例透壁性心肌梗死(2.8%),2例死亡(1.8%),1例急诊手术(0.9%)。77名患者有随访数据(大于或等于1年):68名患者(92%)心绞痛症状改善[49名患者(65%)无心绞痛]。在平均23±10个月的随访期间,有2例心肌梗死和3例死亡。14名患者(17%)出现了临床明显的复发。14名患者中有13名成功进行了再次血管成形术。3名患者在随访期间接受了搭桥手术(其中2名患者在第二次成功血管成形术后复发;1名患者在择期手术期间死亡)。经皮腔内冠状动脉成形术可在70岁以上患者中进行,成功率高,并发症发生率可接受,临床明显复发率相对较低,应被视为选定老年患者的一种治疗方式和替代方法。