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75岁及以上患者冠状动脉成形术和冠状动脉搭桥手术的初始及长期结果

Initial and long-term results of coronary angioplasty and coronary bypass surgery in patients of 75 or older.

作者信息

Bonnier H, de Vries C, Michels R, el Gamal M

机构信息

Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands.

出版信息

Br Heart J. 1993 Aug;70(2):122-5. doi: 10.1136/hrt.70.2.122.

Abstract

OBJECTIVE--To evaluate clinical outcome after percutaneous transluminal coronary angioplasty (PTCA) or coronary artery bypass grafting (CABG) in patients of 75 or older who underwent either procedure between 1980 and 1987. SUBJECTS--93 patients aged 75-89 with angina pectoris class III-IV (Canadian Cardiovascular Society) who underwent PTCA and 81 patients aged 75-84 with angina class III-IV who underwent CABG. Follow up was 8.2 years in the PTCA group and 8.3 years in the CABG group. MAIN OUTCOME MEASURES--In-hospital complications and survival at follow up. RESULTS--Primary success rate for PTCA was 84% (78/93). Two patients died, two had emergency CABG, three had a myocardial infarction, and one had a cerebrovascular accident. PTCA failed in seven patients (five underwent elective CABG and two were treated conservatively). Median hospital stay was 4.3 days. Primary success rate for CABG was 63% (53/81). Six patients died, two had a cerebrovascular accident, eight had a myocardial infarction, 10 had a rethoracotomy, and four the adult respiratory distress syndrome. Median hospital stay was 14.2 days. In the PTCA group during follow up eight patients died, three had a non-fatal myocardial infarction, two had elective CABG, 10 had repeat PTCA, and four had recurrence of angina. Sixty four patients were free of angina (69%). In the CABG group during follow up eight patients died, one had a non-fatal myocardial infarction, six had PTCA, and three had recurrence of angina. Fifty seven patients were free of angina AP (70%). Actuarial survival after 10 years was 92% for PTCA and 91% for CABG. CONCLUSIONS--PTCA is safe in elderly patients. The complication rate is lower and hospital stay significantly shorter compared with CABG (p < 0.05). Long-term follow up showed no significant difference between PTCA and CABG.

摘要

目的——评估1980年至1987年间接受经皮腔内冠状动脉成形术(PTCA)或冠状动脉旁路移植术(CABG)的75岁及以上患者的临床结局。对象——93例年龄在75 - 89岁、患有III - IV级心绞痛(加拿大心血管学会分级)的患者接受了PTCA,81例年龄在75 - 84岁、患有III - IV级心绞痛的患者接受了CABG。PTCA组的随访时间为8.2年,CABG组为8.3年。主要观察指标——住院并发症及随访时的生存率。结果——PTCA的首次成功率为84%(78/93)。2例患者死亡,2例接受急诊CABG,3例发生心肌梗死,1例发生脑血管意外。7例患者PTCA失败(5例接受择期CABG,2例接受保守治疗)。中位住院时间为4.3天。CABG的首次成功率为63%(53/81)。6例患者死亡,2例发生脑血管意外,8例发生心肌梗死,10例接受再次开胸手术,4例发生成人呼吸窘迫综合征。中位住院时间为14.2天。在PTCA组随访期间,8例患者死亡,3例发生非致命性心肌梗死,2例接受择期CABG,10例接受重复PTCA,4例心绞痛复发。64例患者无心绞痛(69%)。在CABG组随访期间,8例患者死亡,1例发生非致命性心肌梗死,6例接受PTCA,3例心绞痛复发。57例患者无心绞痛(70%)。PTCA术后10年的精算生存率为92%,CABG为91%。结论——PTCA在老年患者中是安全的。与CABG相比,并发症发生率更低,住院时间显著更短(p < 0.05)。长期随访显示PTCA和CABG之间无显著差异。

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