Koda Masao, Furuya Takeo, Saito Junya, Ijima Yasushi, Kitamura Mitsuhiro, Ohtori Seiji, Orita Sumihisa, Inage Kazuhide, Abe Tetsuya, Noguchi Hiroshi, Funayama Toru, Kumagai Hiroshi, Miura Kosei, Nagashima Katsuya, Yamazaki Masashi
Departments of Orthopedic Surgery, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 805-8575, Japan.
Chiba University Graduate School of Medicine, Chiba, Japan.
Eur Spine J. 2018 Jun;27(6):1393-1400. doi: 10.1007/s00586-018-5505-4. Epub 2018 Feb 14.
Addition of posterior instrumented fusion to laminoplasty (posterior decompression with instrumented fusion: PDF) can improve the surgical outcome of patients with K-line (-) cervical ossification of the longitudinal ligament (OPLL) compared with laminoplasty alone. We sought to elucidate the factors that are significantly associated with a better outcome after PDF for K-line (-) OPLL.
The present study included 38 patients who underwent PDF for K-line (-) OPLL and were followed up for at least 1 year after surgery. Clinical outcome was assessed using Japanese Orthopedic Association (JOA) scores for cervical myelopathy and the recovery rate was calculated. Patients who belonged to the upper quartile of all the patients according to rank order of the JOA score recovery rate were considered to have a good outcome. The correlations between good outcome, patient factors and imaging assessments were analyzed statistically.
Univariate analyses showed that postoperative conversion of K-line from (-) to (+) (p = 0.004), no increase in the sagittal vertical axis from the center of gravity of the head to C7 (p = 0.07), and a lower grade of preoperative intramedullary T2-signal intensity (p = 0.03) were candidates for the association. Stepwise logistic regression analysis revealed that postoperative K-line conversion from (-) to (+) is an independent factor that is significantly associated with a better surgical outcome (p = 0.04).
Postoperative K-line conversion from (-) to (+) is a factor independently associated with a better surgical outcome. These slides can be retrieved under Electronic Supplementary material.
与单纯椎板成形术相比,在椎板成形术基础上加用后路器械融合术(后路减压并器械融合术:PDF)可改善K线(-)型颈椎后纵韧带骨化症(OPLL)患者的手术效果。我们试图阐明与K线(-)型OPLL患者接受PDF术后获得更好疗效显著相关的因素。
本研究纳入38例行PDF治疗K线(-)型OPLL的患者,术后至少随访1年。采用日本骨科学会(JOA)颈椎病评分评估临床疗效并计算恢复率。根据JOA评分恢复率的排序,将所有患者中处于上四分位数的患者视为疗效良好。对疗效良好情况、患者因素和影像学评估之间的相关性进行统计学分析。
单因素分析显示,K线术后由(-)转为(+)(p = 0.004)、从头部重心到C7矢状垂直轴无增加(p = 0.07)以及术前脊髓内T2信号强度较低(p = 0.03)可能存在相关性。逐步逻辑回归分析显示,术后K线由(-)转为(+)是与更好手术疗效显著相关的独立因素(p = 0.04)。
术后K线由(-)转为(+)是与更好手术疗效独立相关的因素。这些幻灯片可在电子补充材料中获取。