Denaro Vincenzo, Longo Umile Giuseppe, Berton Alessandra, Salvatore Giuseppe, Denaro Luca
Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Alvaro del Portillo, 200, 00128, Trigoria, Rome, Italy.
Department of Neurosurgery, University-Hospital of Padua, Via Giustiniani, 5, Padua, Italy.
Eur Spine J. 2015 Nov;24 Suppl 7:826-31. doi: 10.1007/s00586-015-4298-y. Epub 2015 Nov 4.
Surgical management of patients with multilevel CSM aims to decompress the spinal cord and restore the normal sagittal alignment. The literature lacks of high level evidences about the best surgical approach. Posterior decompression and stabilization in lordosis allows spinal cord back shift, leading to indirect decompression of the anterior spinal cord. The purpose of this study was to investigate the efficacy of posterior decompression and stabilization in lordosis for multilevel CSM.
36 out of 40 patients were clinically assessed at a mean follow-up of 5, 7 years. Outcome measures included EMS, mJOA Score, NDI and SF-12. Patients were asked whether surgery met their expectations and if they would undergo the same surgery again. Bone graft fusion, instrumental failure and cervical curvature were evaluated. Spinal cord back shift was measured and correlation with EMS and mJOA score recovery rate was analyzed.
All scores showed a significative improvement (p < 0.001), except the SF12-MCS (p > 0.05). Ninety percent of patients would undergo the same surgery again. There was no deterioration of the cervical alignment, posterior grafted bones had completely fused and there were no instrument failures. The mean spinal cord back shift was 3.9 mm (range 2.5-4.5 mm). EMS and mJOA recovery rates were significantly correlated with the postoperative posterior cord migration (P < 0.05).
Posterior decompression and stabilization in lordosis is a valuable procedure for patients affected by multilevel CSM, leading to significant clinical improvement thanks to the spinal cord back shift. Postoperative lordotic alignment of the cervical spine is a key factor for successful treatment.
多节段脊髓型颈椎病(CSM)患者的手术治疗旨在减压脊髓并恢复正常矢状位对线。关于最佳手术方法,文献中缺乏高级别证据。后凸位的后路减压及稳定术可使脊髓后移,从而实现脊髓前方的间接减压。本研究的目的是探讨后凸位后路减压及稳定术治疗多节段CSM的疗效。
40例患者中有36例在平均5.7年的随访时接受了临床评估。结果指标包括欧洲脊髓损伤量表(EMS)、改良日本骨科学会(mJOA)评分、颈部功能障碍指数(NDI)和简明健康调查量表(SF-12)。询问患者手术是否符合其期望以及是否会再次接受相同手术。评估植骨融合、内固定失败情况及颈椎曲度。测量脊髓后移情况,并分析其与EMS及mJOA评分恢复率的相关性。
除SF-12的精神健康分量表(MCS)外(p>0.05),所有评分均有显著改善(p<0.001)。90%的患者会再次接受相同手术。颈椎对线无恶化,后路植骨完全融合,无内固定失败。脊髓平均后移3.9mm(范围2.5 - 4.5mm)。EMS和mJOA恢复率与术后脊髓后移显著相关(P<0.05)。
后凸位后路减压及稳定术对多节段CSM患者是一种有价值的手术方法,由于脊髓后移可导致显著的临床改善。颈椎术后的后凸对线是治疗成功的关键因素。