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结直肠癌肝转移:治疗模式概述,强调消融的作用。

Colorectal Liver Metastasis: Overview of Treatment Paradigm Highlighting the Role of Ablation.

机构信息

1 University of Miami Miller School of Medicine, 1475 NW 12th Ave, Ste C080, Miami, FL 33136.

2 Miami Cardiac and Vascular Institute, Miami, FL.

出版信息

AJR Am J Roentgenol. 2018 Apr;210(4):883-890. doi: 10.2214/AJR.17.18574. Epub 2018 Feb 15.

DOI:10.2214/AJR.17.18574
PMID:29446675
Abstract

OBJECTIVE

The objective of this article is to discuss the current treatment options for colorectal cancer (CRC) liver metastases and the role of ablation.

CONCLUSION

A randomized control trial of ablation combined with chemotherapy showed improved overall survival compared with chemotherapy alone. Local recurrence rates are comparable to those associated with resection when ablative margins of more than 5 mm are achieved and target lesions are smaller than 3 cm. In patients with unresectable disease, ablation for curative intent should be considered.

摘要

目的

本文旨在讨论结直肠癌(CRC)肝转移的当前治疗选择和消融的作用。

结论

消融联合化疗的随机对照试验显示,与单独化疗相比,总生存期有所改善。当达到 5 毫米以上的消融边缘且靶病变小于 3 厘米时,消融的局部复发率与与切除术相关的局部复发率相当。对于不可切除的疾病患者,应考虑消融作为治愈性治疗。

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