Machinskaya R I, Rozovskaya R I, Kurgansky A V, Pechenkova E V
Fiziol Cheloveka. 2016 May-Jun;42(3):56-73.
A pattern of cortical functional connectivity in the source space was studied in a group of right-handed adult participants (N = 44:17 women, 27 men, aged M = 29.61 ± 6.45 years) who retained in their working memory (WM) traces of realistic pictures of positive, neutral, and negative emotional valence while in their working memory (WM) while performing same different task in which participants had to compare an etalon picture against a target picture that followed after a specified delay. A coherence (COH) between pairs of cortical sources chosen in advance according to fMRI data was estimated in the theta frequency range for the period of time preceding the etalon stimulus, distinct sets of functional links are found. The links of the first type that presumably reflect the involvement of sustained attention were between the dorsal anterior cingulate cortex, the prefrontal areas, and temporal areas of the right hemispheres. When compared to the rest period, links of this type showed strengthening not only during the retention period but also during the period preceding the etalon picture. The links of the second type presumably reflecting a progressive neocortex-to-hippocampus functional integration with increasing memory load and strengthened exclusively during retention period. Those links were between parietal, temporal and prefrontal cortices in the lateral surface of both hemispheres with the additional inclusion of the posterior cingulate cortex and the medial parietal cortex in the left hemisphere. An impact of emotional valence onto the strength and topography of the functional links of the second type was found. In the left hemisphere, an increase in the strength of cortical interaction was more pronounced for pictures of positive valence than for pictures of either neutral or negative valences. When compared to the pictures of neutral valence, the retention of pictorial information of both positive and negative valence showed some extraneous integration of the cortical areas for the theta rhythm. This finding might be related to the additional load exerted by emotionally colored pictures onto the mechanisms of short-time retention of visual information.
在一组右利手成年参与者（N = 44：17名女性，27名男性，年龄M = 29.61±6.45岁）中研究了源空间中的皮质功能连接模式。这些参与者在工作记忆（WM）中保留正性、中性和负性情绪效价的真实图片的痕迹，同时在执行相同-不同任务时，参与者必须将标准图片与在特定延迟后出现的目标图片进行比较。根据功能磁共振成像（fMRI）数据预先选择的皮质源对之间的相干性（COH）在标准刺激之前的时间段内的θ频率范围内进行估计，发现了不同的功能连接组。第一种类型的连接可能反映持续注意力的参与，存在于右半球的背侧前扣带回皮质、前额叶区域和颞叶区域之间。与休息期相比，这种类型的连接不仅在保持期增强，而且在标准图片出现之前的时期也增强。第二种类型的连接可能反映随着记忆负荷增加新皮质与海马体之间逐渐增强的功能整合，并且仅在保持期增强。这些连接存在于两个半球外侧表面的顶叶、颞叶和前额叶皮质之间，左半球还额外包括后扣带回皮质和内侧顶叶皮质。发现情绪效价对第二种类型功能连接的强度和拓扑结构有影响。在左半球，正性效价图片比中性或负性效价图片的皮质相互作用强度增加更明显。与中性效价图片相比，正性和负性效价图片的图像信息保留显示出θ节律下皮质区域的一些额外整合。这一发现可能与带有情感色彩的图片对视觉信息短时保留机制施加的额外负荷有关。
