Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Department of Society and Health, Mahidol University, Salaya Campus, Bangkok, Thailand.
PLoS One. 2018 Feb 15;13(2):e0193054. doi: 10.1371/journal.pone.0193054. eCollection 2018.
Thailand has one of the world's highest prevalence of cervical cancer, mainly caused by the human papillomavirus (HPV). HPV infections can successfully be prevented by vaccination, which is available at a cost but not yet implemented in the national vaccination program. Parents play a critical role in deciding whether to vaccinate their child against HPV. Thus, the aim was to examine the association between parents' knowledge, beliefs, and acceptance of the HPV vaccination for their daughters, considering their socio-demographics and religious beliefs. A cross-sectional design was used among three schools in Thailand: Nakorn Phatom province (suburban) and Bangkok (urban). Parents of 9-12-year-old daughters completed the questionnaires, guided by the Health Belief Model. In total, 359 parents completed the questionnaires; of those, 301 were included in the final analyses. The ordinary least squares (OLS) regression analysis showed that background knowledge of HPV and the HPV vaccine was positively related to knowledge of HPV and cervical cancer. For beliefs, knowledge was positively associated with susceptibility (i.e., parents' perceived risk of an HPV infection/ related disease), severity, and benefit. However, knowledge was not significantly related to barriers. For acceptance, higher susceptibility and benefit were related to higher acceptance, and greater knowledge was associated with higher acceptance. Thus, we found associations between parents' knowledge, beliefs, and acceptance of the HPV vaccination for their daughters, considering their socio-demographics and religious beliefs. Parents, who reported religion as important, as opposed to those who did not, were more favorable toward the HPV vaccination. Four out of ten mothers had never undergone a cervical cancer screening, but most had accepted previous childhood vaccinations for their daughters. The overall acceptance of the vaccine was high, and we believe our results are promising for future implementation of the HPV vaccination in the national childhood vaccination program in Thailand.
泰国的宫颈癌发病率居世界之首,主要由人乳头瘤病毒(HPV)引起。HPV 感染可通过疫苗接种有效预防,该疫苗已上市,但尚未纳入国家免疫规划。父母在决定是否为子女接种 HPV 疫苗方面起着关键作用。因此,本研究旨在考察父母对 HPV 疫苗接种的知识、信念和接受程度与其社会人口统计学和宗教信仰之间的关系。本研究采用横断面设计,在泰国的 3 所学校(那空巴吞府[郊区]和曼谷[城市])中进行:纳空巴吞府学校、曼谷的三仓学校和吞武里学校。9-12 岁女童的父母在健康信念模型的指导下填写问卷。共 359 名父母完成了问卷,其中 301 名被纳入最终分析。普通最小二乘法(OLS)回归分析表明,HPV 和 HPV 疫苗的背景知识与 HPV 和宫颈癌知识呈正相关。在信念方面,知识与易感性(即父母对 HPV 感染/相关疾病的感知风险)、严重性和获益呈正相关。然而,知识与障碍无显著相关性。在接受程度方面,较高的易感性和获益与较高的接受程度相关,而更多的知识与更高的接受程度相关。因此,我们发现父母对 HPV 疫苗接种的知识、信念和接受程度与其社会人口统计学和宗教信仰有关。与不认为宗教重要的父母相比,认为宗教重要的父母对 HPV 疫苗接种更支持。40%的母亲从未进行过宫颈癌筛查,但大多数母亲都接受了为女儿接种的以前的儿童疫苗。疫苗总体接种率较高,我们相信我们的研究结果对未来在泰国全国儿童免疫规划中实施 HPV 疫苗接种具有重要意义。