Department of Cancer Control and Population Health, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.
Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Cancer Prev Res (Phila). 2023 Mar 1;16(3):133-138. doi: 10.1158/1940-6207.CAPR-22-0412.
Human papillomavirus (HPV) vaccination was introduced in the National Immunization Program (NIP) in Korea targeting girls aged 12 years to receive two doses of HPV vaccine to prevent cervical cancer. This study aimed to evaluate the factors that may influence parental decision to inoculate their daughters in Korea. A cross-sectional survey was conducted in 2020 by interviewing the parents of 2,000 nationally representative girls eligible for HPV NIP. By the daughters' status of HPV vaccination, the probabilities for each variable were compared with evaluate the factors that could affect parents' decision to inoculate their daughters with HPV vaccines. Compared with parents who were not vaccinated with HPV, parents who were vaccinated with HPV were 2.40 times more likely to decide to vaccinate their daughters with HPV. Parents who regularly undergo cervical cancer screening were 1.39 times more likely to decide to vaccinate their daughters with HPV than parents who do not receive regular checkups. Parents' perceived knowledge and perceived risk had a significant impact on their decision to vaccinate their daughters with HPV vaccines. Parents who had strong belief that HPV vaccine is safe in terms of adverse effects were 10 times more likely to decide to vaccinate their daughters against HPV. Parental factors including HPV-related health behavior and awareness were found to be associated with parental decision to vaccinate their daughters against HPV. To improve HPV vaccine uptake at 12 years, it is required to improve parental awareness on HPV through public communication supported by scientific-based evidence.
Parental HPV vaccination and maternal regular cervical cancer screening were positively associated with parental decision to vaccinate their daughters against HPV. Parents' perceived knowledge of HPV vaccination and perceived risk of cervical cancer play an important role in determining whether their 12-year-old daughters will be vaccinated against HPV.
人乳头瘤病毒（HPV）疫苗接种已纳入韩国国家免疫计划（NIP），目标人群为 12 岁女孩，接种两剂 HPV 疫苗以预防宫颈癌。本研究旨在评估可能影响韩国父母为其女儿接种疫苗的决策的因素。2020 年，通过对 2000 名有资格接种 HPV NIP 的全国代表性女孩的父母进行访谈，开展了一项横断面调查。根据女儿 HPV 疫苗接种状况，比较各变量的概率，以评估可能影响父母决定为女儿接种 HPV 疫苗的因素。与未接种 HPV 疫苗的父母相比，接种过 HPV 疫苗的父母更有可能决定为女儿接种 HPV 疫苗，其可能性是前者的 2.40 倍。与未定期接受宫颈癌筛查的父母相比，定期接受宫颈癌筛查的父母更有可能决定为女儿接种 HPV 疫苗，其可能性是前者的 1.39 倍。父母对 HPV 疫苗的认知和感知风险对其决定为女儿接种 HPV 疫苗有显著影响。父母认为 HPV 疫苗在不良反应方面安全的可能性是决定为女儿接种 HPV 疫苗的 10 倍。父母的 HPV 相关健康行为和意识等因素与父母决定为女儿接种 HPV 疫苗有关。为了提高 12 岁女孩 HPV 疫苗接种率，需要通过科学证据支持的公共宣传来提高父母对 HPV 的认识。
父母接种 HPV 疫苗和母亲定期进行宫颈癌筛查与父母决定为其女儿接种 HPV 疫苗呈正相关。父母对 HPV 疫苗接种的认知和对宫颈癌的感知风险在决定其 12 岁女儿是否接种 HPV 疫苗方面发挥着重要作用。
