School of Optometry and Ophthalmology, Tianjin Medical University Eye Hospital, Tianjin, China.
College of Optometry, Nova Southeastern University, Fort Lauderdale, Florida, United States of America.
PLoS One. 2018 Feb 15;13(2):e0193215. doi: 10.1371/journal.pone.0193215. eCollection 2018.
Pattern-related visual stress (PRVS) refers to the perceptual difficulties experienced by some individuals when exposed to high contrast striped patterns. People with PRVS were reported to have reduced sensitivity to global motion at baseline testing and the difference disappears at a second estimate. The present study was to investigate the effect of practice on global motion threshold in adults with and without PRVS.
A total of 101 subjects were recruited and the Wilkins & Evans Pattern Glare Test was used to determine if a subject had PRVS. The threshold to detect global motion was measured with a random dot kinematogram. Each subject was measured 5 times at the first visit and again a month later. Receiver operating characteristic (ROC) curve analysis was applied to show the agreement between the two tests.
Twenty-nine subjects were classified as having PRVS and 72 were classified as normal. At baseline, the threshold to detect global motion was significantly higher in subjects with PRVS (0.832 ± 0.098 vs. 0.618 ± 0.228, p < 0.001). After 5 sessions, the difference between the normal and subjects with PRVS increased (0.767 ± 0.170 vs. 0.291 ± 0.149, p < 0.001). In ROC analysis, the area under the curve (AUC) improved from 0.792 at baseline to 0.964 at the fifth session. After a one-month break, the difference between normal and subjects with PRVS was still significant (0.843 ± 0.169 vs. 0.407 ± 0.216, p < 0.001) and the AUC was 0.875.
The ability to detect global motion is impaired in persons with PRVS and the difference increased after additional sessions of practice.
模式相关视疲劳（PRVS）是指一些人在暴露于高对比度条纹图案时所经历的感知困难。据报道，有 PRVS 的人在基线测试时对全局运动的敏感性降低，而在第二次估计时差异消失。本研究旨在调查有和没有 PRVS 的成年人在练习后对全局运动阈值的影响。
共招募了 101 名受试者，并用 Wilkins & Evans 模式眩光测试来确定受试者是否有 PRVS。使用随机点运动图来测量检测全局运动的阈值。每位受试者在第一次就诊时测量 5 次，一个月后再次测量。应用受试者工作特征（ROC）曲线分析来显示两种测试之间的一致性。
29 名受试者被归类为有 PRVS，72 名受试者被归类为正常。在基线时，有 PRVS 的受试者检测全局运动的阈值明显更高（0.832±0.098 与 0.618±0.228，p<0.001）。经过 5 次训练后，正常受试者和有 PRVS 受试者之间的差异增加（0.767±0.170 与 0.291±0.149，p<0.001）。在 ROC 分析中，曲线下面积（AUC）从基线时的 0.792 提高到第 5 次时的 0.964。经过一个月的休息后，正常受试者和有 PRVS 受试者之间的差异仍然显著（0.843±0.169 与 0.407±0.216，p<0.001），AUC 为 0.875。
有 PRVS 的人检测全局运动的能力受损，经过额外的训练后差异增加。
