Syrop C H, Halme J
Fertil Steril. 1986 Oct;46(4):631-5. doi: 10.1016/s0015-0282(16)49640-8.
The effects of peritoneal fluid or its cellular components on human oocyte fertilization and cleavage cannot be studied directly. This report explores the association of laparoscopically obtained peritoneal fluid volume, macrophage count, and concentration of 124 infertility patients and their first occurrence of pregnancy during a 2-year follow-up period. Endometriosis patients who achieved pregnancy had a significantly lower mean fluid volume than those remaining nonpregnant. In patients with endometriosis, a fluid volume significantly less than the mean for all endometriosis patients carries a significantly greater chance of pregnancy. The time required for the occurrence of pregnancy in patients with endometriosis appears influenced by peritoneal fluid volume. Peritoneal fluid of patients with endometriosis, via an as yet unknown mechanism or substance, appears to be associated with reduced fertility.
无法直接研究腹腔液或其细胞成分对人类卵母细胞受精和分裂的影响。本报告探讨了124例不孕患者通过腹腔镜获取的腹腔液体积、巨噬细胞计数和浓度与她们在2年随访期内首次怀孕之间的关联。成功怀孕的子宫内膜异位症患者的平均液体量明显低于仍未怀孕的患者。在子宫内膜异位症患者中,液体量显著低于所有子宫内膜异位症患者的平均值时,怀孕的几率会显著增加。子宫内膜异位症患者怀孕所需的时间似乎受腹腔液体积的影响。子宫内膜异位症患者的腹腔液似乎通过一种尚不清楚的机制或物质与生育能力降低有关。