Rocca B J, Gini A, Calandra C, Ginori A, Crivelli F
Pathology Unit, ASST Valle Olona, Busto Arsizio, Italy.
Pathology Unit, Ospedale Civico di Carrara, Italy.
Pathologica. 2017 Dec;109(4):384-388.
Malignancies of the parotid gland are relatively uncommon, accounting for only 3-6% of all head and neck cancers. Most of them are primary neoplasms, metastases are uncommon. Renal cell carcinoma (RCC) represents 3% of adult malignancies, the clear cell type comprises up to 70% of all RCC. RCC has an unpredictable behavior and the unique potential to metastasize to nearly every organ in the body. Though not as frequent, metastatic RCC to the head and neck has been identified in the thyroid, salivary glands, skull base, sinuses, pharynx, tonsils, tongue, lip and skin. Metastasis to the parotid gland is very rare. Here, we report the case of a clear cell type RCC metastatic to the parotid gland and mimicking a primary clear cell oncocytoma. Differential diagnoses and a brief review of the literature are added.
腮腺恶性肿瘤相对少见，仅占所有头颈癌的3% - 6%。其中大多数为原发性肿瘤，转移瘤不常见。肾细胞癌（RCC）占成人恶性肿瘤的3%，透明细胞型占所有RCC的70%。RCC行为难以预测，具有转移至体内几乎每个器官的独特可能性。虽然不常见，但已发现甲状腺、唾液腺、颅底、鼻窦、咽、扁桃体、舌、唇和皮肤等部位发生头颈部转移性RCC。转移至腮腺极为罕见。在此，我们报告一例透明细胞型RCC转移至腮腺并酷似原发性透明细胞嗜酸细胞瘤的病例。此外还增加了鉴别诊断及文献简要综述。
