Broggi G, Reggio E, Giuliano L, Palmucci S, Caltabiano R, Lanzafame S
Department G.F. Ingrassia, Section of Anatomic Pathology, University of Catania, Italy.
Department G.F. Ingrassia, Section of Neurosciences, University of Catania, Italy.
Pathologica. 2017 Dec;109(4):418-420.
Sarcoidosis is a multisystemic granulomatous disease characterized by the presence of noncaseating granulomas, the exact etiology of which is yet to be determined. Most of patients show granulomas located in the lungs or in the related lymph nodes. However, lesions can affect any organ. Noncaseating granulomas are not a pathognomonic sign of sarcoidosis, being observed also in other diseases, therefore the diagnosis is often of exclusion. We report a case of sarcoidosis with parotid gland involvement in the context of a Heerfordt syndrome, discussing about its clinical presentation, pathogenesis, pathology and differential diagnosis with other granulomatous diseases.
结节病是一种多系统肉芽肿性疾病，其特征为存在非干酪样肉芽肿，确切病因尚待确定。大多数患者的肉芽肿位于肺部或相关淋巴结。然而，病变可累及任何器官。非干酪样肉芽肿并非结节病的特异性体征，在其他疾病中也可观察到，因此诊断通常需排除其他疾病。我们报告一例结节病累及腮腺并伴有黑尔福特综合征的病例，讨论其临床表现、发病机制、病理及与其他肉芽肿性疾病的鉴别诊断。
