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Commentary: Maintenance of CD8 T Memory Lymphocytes in the Spleen but Not in the Bone Marrow Is Dependent on Proliferation.评论：脾脏中而非骨髓中的CD8 T记忆淋巴细胞的维持依赖于增殖。
Front Immunol. 2018 Feb 1;9:122. doi: 10.3389/fimmu.2018.00122. eCollection 2018.
2
Maintenance of CD8 memory T lymphocytes in the spleen but not in the bone marrow is dependent on proliferation.脾脏中CD8记忆性T淋巴细胞的维持依赖于增殖，而骨髓中的则不然。
Eur J Immunol. 2017 Nov;47(11):1900-1905. doi: 10.1002/eji.201747063. Epub 2017 Oct 11.
3
IL-15-dependent upregulation of GITR on CD8 memory phenotype T cells in the bone marrow relative to spleen and lymph node suggests the bone marrow as a site of superior bioavailability of IL-15.IL-15 依赖性上调 CD8 记忆表型 T 细胞在骨髓中的 GITR 表达水平，相对脾脏和淋巴结，提示骨髓为 IL-15 具有更高生物利用度的部位。
J Immunol. 2012 Jun 15;188(12):5915-23. doi: 10.4049/jimmunol.1103270. Epub 2012 May 11.
4
Maintenance of memory CD8 T cells: Divided over division.维持记忆性 CD8 T 细胞：分裂与分化之间的权衡。
Eur J Immunol. 2017 Nov;47(11):1875-1879. doi: 10.1002/eji.201747249.
5
IL-15 inhibits IL-7Rα expression by memory-phenotype CD8⁺ T cells in the bone marrow.IL-15 通过骨髓中记忆表型 CD8+T 细胞抑制 IL-7Rα 的表达。
Eur J Immunol. 2012 May;42(5):1129-39. doi: 10.1002/eji.201142019.
6
Maintenance of long-term tumour-specific T-cell memory by residual dormant tumour cells.残留的休眠肿瘤细胞维持长期肿瘤特异性T细胞记忆。
Immunology. 2005 Jul;115(3):325-36. doi: 10.1111/j.1365-2567.2005.02163.x.
7
Effect of Cyclophosphamide Treatment on Central and Effector Memory T Cells in Mice.环磷酰胺处理对小鼠中枢和效应记忆 T 细胞的影响。
Int J Toxicol. 2018 Sep/Oct;37(5):373-382. doi: 10.1177/1091581818780128. Epub 2018 Jun 20.
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Differential requirement for B-memory and T-memory cells in adoptive antibody formation in mouse bone marrow.小鼠骨髓中过继性抗体形成对B记忆细胞和T记忆细胞的不同需求。
Immunology. 1982 Apr;45(4):697-704.
9
B and T lymphocyte attenuator regulates CD8+ T cell-intrinsic homeostasis and memory cell generation.B和T淋巴细胞衰减器调节CD8 + T细胞内在的稳态和记忆细胞生成。
Nat Immunol. 2007 Feb;8(2):162-71. doi: 10.1038/ni1418. Epub 2007 Jan 7.
10
GITR-dependent regulation of 4-1BB expression: implications for T cell memory and anti-4-1BB-induced pathology.GITR 依赖性调节 4-1BB 表达：对 T 细胞记忆和抗 4-1BB 诱导的病理的影响。
J Immunol. 2013 May 1;190(9):4627-39. doi: 10.4049/jimmunol.1201854. Epub 2013 Mar 27.

引用本文的文献

1
Short Lifespans of Memory T-cells in Bone Marrow, Blood, and Lymph Nodes Suggest That T-cell Memory Is Maintained by Continuous Self-Renewal of Recirculating Cells.骨髓、血液和淋巴结中记忆 T 细胞的寿命较短，提示循环细胞的连续自我更新维持了 T 细胞记忆。
Front Immunol. 2018 Sep 11;9:2054. doi: 10.3389/fimmu.2018.02054. eCollection 2018.

本文引用的文献

1
Maintenance of memory CD8 T cells: Divided over division.维持记忆性 CD8 T 细胞：分裂与分化之间的权衡。
Eur J Immunol. 2017 Nov;47(11):1875-1879. doi: 10.1002/eji.201747249.
2
Maintenance of CD8 memory T lymphocytes in the spleen but not in the bone marrow is dependent on proliferation.脾脏中CD8记忆性T淋巴细胞的维持依赖于增殖，而骨髓中的则不然。
Eur J Immunol. 2017 Nov;47(11):1900-1905. doi: 10.1002/eji.201747063. Epub 2017 Oct 11.
3
Antigen-inexperienced memory CD8 T cells: where they come from and why we need them.未接触过抗原的记忆性CD8 T细胞：它们的来源及我们需要它们的原因。
Nat Rev Immunol. 2017 Jun;17(6):391-400. doi: 10.1038/nri.2017.34. Epub 2017 May 8.
4
A new mechanism shapes the naïve CD8 T cell repertoire: the selection for full diversity.一种塑造初始CD8 T细胞库的新机制：对完全多样性的选择。
Mol Immunol. 2017 May;85:66-80. doi: 10.1016/j.molimm.2017.01.026. Epub 2017 Mar 8.
5
Editorial: Bone Marrow T Cells at the Center Stage in Immunological Memory.社论：处于免疫记忆核心地位的骨髓T细胞
Front Immunol. 2016 Dec 14;7:596. doi: 10.3389/fimmu.2016.00596. eCollection 2016.
6
The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy.环磷酰胺对免疫系统的影响：对临床癌症治疗的启示。
Cancer Chemother Pharmacol. 2016 Oct;78(4):661-71. doi: 10.1007/s00280-016-3152-1. Epub 2016 Sep 19.
7
Response: Commentary: Memory CD8(+) T Cells Colocalize with IL-7(+) Stromal Cells in Bone Marrow and Rest in Terms of Proliferation and Transcription.回应：评论：记忆性CD8(+) T细胞与骨髓中IL-7(+) 基质细胞共定位，且在增殖和转录方面处于静止状态。
Front Immunol. 2016 Aug 31;7:329. doi: 10.3389/fimmu.2016.00329. eCollection 2016.
8
Two Niches in the Bone Marrow: A Hypothesis on Life-long T Cell Memory.两个骨髓龛：关于终生 T 细胞记忆的假说。
Trends Immunol. 2016 Aug;37(8):503-512. doi: 10.1016/j.it.2016.05.004. Epub 2016 Jul 6.
9
Commentary: Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription.评论：记忆性CD8(+) T细胞与骨髓中IL-7(+) 基质细胞共定位，并在增殖和转录方面处于静止状态。
Front Immunol. 2016 Mar 31;7:102. doi: 10.3389/fimmu.2016.00102. eCollection 2016.
10
Maintenance of memory T cells in the bone marrow: survival or homeostatic proliferation?骨髓中记忆性T细胞的维持：存活还是稳态增殖？
Nat Rev Immunol. 2016 Apr;16(4):271. doi: 10.1038/nri.2016.31. Epub 2016 Mar 21.

Commentary: Maintenance of CD8 T Memory Lymphocytes in the Spleen but Not in the Bone Marrow Is Dependent on Proliferation.

作者信息

Di Rosa Francesca, Rocha Benedita

机构信息

Institute of Molecular Biology and Pathology, Consiglio Nazionale delle Ricerche, c/o Department of Molecular Medicine, Sapienza University, Rome, Italy.

Population Biology Unit, CNRS URA 196, Institut Pasteur, Paris, France.

出版信息

Front Immunol. 2018 Feb 1;9:122. doi: 10.3389/fimmu.2018.00122. eCollection 2018.

DOI:10.3389/fimmu.2018.00122
PMID:29449844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5799279/
Abstract
摘要