Chiang Yuting P, Shimada Yuichi J, Ginns Jonathan, Weiner Shepard D, Takayama Hiroo
Division of Cardiothoracic and Vascular Surgery, Department of Surgery, Columbia University Medical Center, Milstein Hospital Building, 177 Fort Washington Avenue, Suite 7-435, New York, NY, 10032, USA.
Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, USA.
Gen Thorac Cardiovasc Surg. 2018 Apr;66(4):192-200. doi: 10.1007/s11748-018-0895-0. Epub 2018 Feb 15.
Hypertrophic cardiomyopathy (HCM) is the most commonly inherited cardiac disease-recent studies suggest a prevalence as high as 1 in 200. For symptomatic patients with obstructive HCM who are refractory to medical therapy, septal reduction is indicated. Septal myectomy (SM) is considered the gold standard septal reduction technique. However, due to a shortage of surgeons who are experienced in this technique, alcohol septal ablation (ASA) has overtaken SM as the most commonly performed procedure for obstructive HCM. In this review, we summarize the existing literature comparing SM with ASA and describe recent innovations in operative technique, including a detailed description of the approach used at our institution.
肥厚型心肌病(HCM)是最常见的遗传性心脏病——最近的研究表明,其患病率高达1/200。对于药物治疗无效的有症状梗阻性HCM患者,需要进行室间隔减容治疗。室间隔心肌切除术(SM)被认为是室间隔减容的金标准技术。然而,由于缺乏精通此技术的外科医生,酒精室间隔消融术(ASA)已超过SM,成为梗阻性HCM最常用的治疗方法。在本综述中,我们总结了比较SM与ASA的现有文献,并描述了手术技术的最新创新,包括对我们机构所采用方法的详细描述。