Borges Alana Costa, Almeida Paulo César, Furlani Stella M T, Cury Marcelo DE Sousa, Gaur Shantanu
Digestive Endoscopy Department, Zilda Arns Hospital and Maternity, Fortaleza, CE, Brazil.
Biostatistics, Health Sciences Center, State University of Ceará, Fortaleza, CE, Brazil.
Rev Col Bras Cir. 2018;45(1):e1448. doi: 10.1590/0100-6991e-20181448. Epub 2018 Feb 15.
to assess the short-term efficacy, tolerance and complications in high-risk morbidly obese patients treated with an intragastric balloon as a bridge for surgery.
we conducted a post-hoc analysis study in a Brazilian teaching hospital from 2010 to 2014, with 23 adult patients with a BMI of 48kg/m2, who received a single intragastric air or liquid balloon. We defined efficacy as 10% excess weight loss, and complications, as adverse events consequent to the intragastric balloon diagnosed after the initial accommodative period. We expressed the anthropometric results as means ± standard deviation, comparing the groups with paired T / Student's T tests, when appropriate, with p<0.05 considered statistically significant.
the balloons were effective in 91.3% of the patients, remained in situ for an average of 5.5 months and most of them (65.2%) were air-filled, with a mean excess weight loss of 23.7kg±9.7 (excess weight loss 21.7%±8.9) and mean BMI reduction of 8.3kg/m2±3.3. Complications (17.3%) included abdominal discomfort, balloon deflation and late intolerance, without severe cases. Most of the participants (82.7%) did not experience adverse effects. We removed the intragastric balloons in time, without intercurrences, and 52.2% of these patients underwent bariatric surgery within one month.
in our center, intragastric balloons can be successfully used as an initial weight loss procedure, with good tolerance and acceptable complications rates.
评估胃内球囊作为手术桥梁治疗高危病态肥胖患者的短期疗效、耐受性及并发症。
2010年至2014年,我们在巴西一家教学医院进行了一项事后分析研究,纳入23例BMI为48kg/m²的成年患者,他们均接受了单个胃内空气或液体球囊治疗。我们将疗效定义为体重减轻10%,并发症定义为初始适应期后诊断出的胃内球囊相关不良事件。人体测量结果以均值±标准差表示,适当时采用配对T检验/学生T检验比较各组,p<0.05认为具有统计学意义。
球囊在91.3%的患者中有效,平均在位5.5个月,其中大多数(65.2%)为充气式,平均超重减轻23.7kg±9.7(超重减轻21.7%±8.9),平均BMI降低8.3kg/m²±3.3。并发症发生率为17.3%,包括腹部不适、球囊放气和后期不耐受,无严重病例。大多数参与者(82.7%)未出现不良反应。我们及时取出胃内球囊,未发生意外情况,其中52.2%的患者在1个月内接受了减重手术。
在我们中心,胃内球囊可成功用作初始减重程序,耐受性良好且并发症发生率可接受。