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[炎症后色素沉着]

[Post-inflammatory hyperpigmentation].

作者信息

Passeron T

机构信息

Service de dermatologie, CHU Nice, France; INSERM U1065, équipe 12, C3M, Nice, France.

出版信息

Ann Dermatol Venereol. 2016 Dec;143 Suppl 2:S15-S19. doi: 10.1016/S0151-9638(18)30079-6.

DOI:10.1016/S0151-9638(18)30079-6
PMID:29452653
Abstract

Post-inflammatory hyperpigmentation (PIH) is a hyperpigmentation of the skin occurring after and sometimes during an inflammatory process. Although more frequent in dark skinned individuals, PIH can be observed in any type of skin and at all ages. In most case a strong impact on the quality of life of affected individuals is observed. The pathophysiology of PIH remains largely unknown. The activation of the melanocytes occurs in the first week following the inflammation emphasizing the crucial role of early preventive measures. Photoprotection with balanced UVA and UVB protection is required. Visible light could also play a role in PIH but this remains to be demonstrated. Healing topics with anti-inflammatory properties are of interest after a skin procedure. When the risk of PIH is high or when PIH occurs, topical steroids remains the gold standard approach.

摘要

炎症后色素沉着(PIH)是一种在炎症过程之后甚至有时在炎症过程中出现的皮肤色素沉着。尽管PIH在深色皮肤个体中更为常见,但在任何类型的皮肤以及所有年龄段都可能出现。在大多数情况下,会观察到对受影响个体的生活质量有很大影响。PIH的病理生理学在很大程度上仍然未知。黑素细胞的激活发生在炎症后的第一周,这突出了早期预防措施的关键作用。需要进行具有平衡UVA和UVB防护的光保护。可见光也可能在PIH中起作用,但这仍有待证实。在皮肤手术后,具有抗炎特性的愈合主题受到关注。当PIH风险较高或出现PIH时,局部使用类固醇仍然是金标准方法。

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