Lunets E F, Kuchuro S V, Kostiuk V A
Vopr Med Khim. 1986 Jul-Aug;32(4):32-5.
Effect of ascorbate-dependent lipid peroxidation on activity of Mg2+-ATPase was studied in rat brain and liver tissues. Lipid peroxidation was shown to inactivate Mg2+-ATPase in the fraction of "heavy" brain microsomes. The rate of inactivation was directly related to the amount of the primary products of lipid peroxidation, accumulating in membrane lipids. At the same time, more intensive lipid peroxidation, as evidenced by content of diene conjugates and malonic dialdehyde, did not affect the liver Mg2+-ATPase.
在大鼠脑和肝组织中研究了抗坏血酸依赖性脂质过氧化对Mg2 + -ATP酶活性的影响。结果表明，脂质过氧化使脑“重”微粒体部分的Mg2 + -ATP酶失活。失活速率与膜脂中积累的脂质过氧化初级产物的量直接相关。同时，由二烯共轭物和丙二醛含量证明的更强烈的脂质过氧化并未影响肝脏Mg2 + -ATP酶。
