Laboratoire de Pharmacologie, pharmacie clinique et contrôle de qualité des médicaments, Pôle technologie Santé, Faculté de Pharmacie, Université Saint-Joseph de Beyrouth, Beirut, Lebanon.
Faculty of Pharmacy, Saint-Joseph University, Beirut, Lebanon.
Support Care Cancer. 2018 Aug;26(8):2581-2590. doi: 10.1007/s00520-018-4089-1. Epub 2018 Feb 16.
Spiritual well-being was found to have some protective effect against end-of life despair in cancer patients. We aimed at assessing the impact of spirituality on the quality of life, depression, and anxiety of Lebanese cancer patients.
Our observational transversal monocentric study was conducted between January and April 2016 among a convenient sample of 115 Lebanese cancer patients admitted to Hôtel-Dieu de France Hospital (HDF), Beirut-Lebanon. In addition to socio-demographic and clinical data, three questionnaires were used: EORTC QLQ-C30 (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, 3rd version), FACIT-Sp-12 (Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being; The 12-item Spiritual Well-Being Scale, 4th version), and HADS (Hospital Anxiety and Depression Scale). Eighteen patients taking anxiolytic and/or antidepressants were not included in the analysis. The remaining 97 patients were analyzed.
Better emotional and cognitive functioning was seen in patients with higher meaning, peace, faith, and total FACIT scores. Meaning, peace, and total FACIT scores were also higher among patients with better global health status and quality of life. Anxiety as well as depression was significantly associated to all spiritual well-being factors.
Spirituality can improve quality of life and decrease the incidence of anxiety and depression in cancer patients. Our results highlight the need to incorporate spiritual care in healthcare systems.
研究发现，精神幸福感对癌症患者临终前的绝望情绪有一定的保护作用。我们旨在评估灵性对黎巴嫩癌症患者生活质量、抑郁和焦虑的影响。
我们的观察性横断单中心研究于 2016 年 1 月至 4 月在黎巴嫩贝鲁特的法国医院（Hôtel-Dieu de France Hospital）便利样本中进行，共纳入 115 名黎巴嫩癌症患者。除了社会人口学和临床数据外，还使用了三个问卷：EORTC QLQ-C30（欧洲癌症研究与治疗组织生活质量问卷，第 3 版）、FACIT-Sp-12（慢性疾病治疗的功能评估-精神幸福感；第 4 版 12 项精神幸福感量表）和 HADS（医院焦虑和抑郁量表）。18 名服用抗焦虑药和/或抗抑郁药的患者未纳入分析。对其余 97 名患者进行了分析。
具有更高意义、平静、信仰和更高总分的 FACIT 评分的患者具有更好的情感和认知功能。在全球健康状况和生活质量较好的患者中，意义、平静和总 FACIT 评分也更高。焦虑和抑郁与所有精神幸福感因素显著相关。
灵性可以改善癌症患者的生活质量，降低焦虑和抑郁的发生率。我们的结果强调了在医疗保健系统中纳入精神关怀的必要性。
