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大豆疫霉效应物调控与寄主免疫的斗争。

Phytophthora sojae effectors orchestrate warfare with host immunity.

机构信息

Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.

Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.

出版信息

Curr Opin Microbiol. 2018 Dec;46:7-13. doi: 10.1016/j.mib.2018.01.008. Epub 2018 Feb 22.

Abstract

Phytophthora sojae is one of the most damaging plant pathogens of soybean. To aid establishment of a compatible interaction with its host, P. sojae deploys many secreted effectors. These effectors act either in the apoplastic space to cope with hostile conditions or inside of host cells to reprogram host physiology favoring pathogen growth. Effectors have been used as molecular probes, which revealed in Phytophthora that effectors execute their virulence function via manipulating host targets. In addition, recent studies have discovered 'pseudo-effectors' in Phytophthora that act as decoys to shield virulence effectors from host defense, a new paradigm in plant-pathogen interactions.

摘要

大豆疫霉是大豆最具破坏性的植物病原体之一。为了帮助与宿主建立相容的相互作用,大豆疫霉部署了许多分泌效应子。这些效应子要么在质外体空间中发挥作用以应对恶劣条件,要么在宿主细胞内发挥作用以重新编程宿主生理学,从而促进病原体的生长。效应子已被用作分子探针,这揭示了在疫霉中,效应子通过操纵宿主靶标来执行其毒性功能。此外,最近的研究在疫霉中发现了“伪效应子”,它们作为诱饵,使毒性效应子免受宿主防御的影响,这是植物-病原体相互作用中的一个新范例。

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