Department of Orthodontics, University of Damascus Dental School, Damascus, Syria.
Department of Oral Medicine, University of Damascus Dental School, Damascus, Syria.
Head Face Med. 2018 Feb 17;14(1):4. doi: 10.1186/s13005-018-0161-9.
To evaluate the effectiveness of two minimally invasive surgical procedures in the acceleration of canine retraction: piezocision and laser-assisted flapless corticotomy (LAFC).
Trial design: A single-centre randomized controlled trial with a compound design (two-arm parallel-group design and a split-mouth design for each arm).
36 Class II division I patients (12 males, 24 females; age range: 15 to 27 years) requiring first upper premolars extraction followed by canine retraction.
piezocision group (PG; n = 18) and laser-assisted flapless corticotomy group (LG; n = 18). A split-mouth design was applied for each group where the flapless surgical intervention was randomly allocated to one side and the other side served as a control side.
the rate of canine retraction (primary outcome), anchorage loss and canine rotation, which were assessed at 1, 2, 3 and 4 months following the onset of canine retraction. Also the duration of canine retraction was recorded. Random sequence: Computer-generated random numbers. Allocation concealment: sequentially numbered, opaque, sealed envelopes. Blinding: Single blinded (outcomes' assessor).
Seventeen patients in each group were enrolled in the statistical analysis. The rate of canine retraction was significantly greater in the experimental side than in the control side in both groups by two-fold in the first month and 1.5-fold in the second month (p < 0.001). Also the overall canine retraction duration was significantly reduced in the experimental side as compared with control side in both groups about 25% (p ≤ 0.001). There were no significant differences between the experimental and the control sides regarding loss of anchorage and upper canine rotation in both groups (p > 0.05). There were no significant differences between the two flapless techniques regarding the studied variables during all evaluation times (p > 0.05).
Piezocision and laser-assisted flapless corticotomy appeared to be effective treatment methods for accelerating canine retraction without any significant untoward effect on anchorage or canine rotation during rapid retraction.
ClinicalTrials.gov (Identifier: NCT02606331 ).
评估两种微创外科手术在加速犬齿回缩中的效果：超声骨刀切割和激光辅助无瓣皮质切开术（LAFC）。
试验设计：一项单中心随机对照试验，采用复合设计（双臂平行组设计和每个臂的劈裂口设计）。
36 例 II 类 1 分类患者（12 名男性，24 名女性；年龄范围：15 至 27 岁），需要拔除上颌第一前磨牙，然后进行犬齿回缩。
超声骨刀组（PG；n=18）和激光辅助无瓣皮质切开组（LG；n=18）。每个组都应用劈裂口设计，其中无瓣手术干预随机分配到一侧，另一侧作为对照侧。
犬齿回缩率（主要结局）、支抗丧失和犬齿旋转，在犬齿回缩开始后 1、2、3 和 4 个月进行评估。还记录了犬齿回缩的持续时间。随机序列：计算机生成的随机数。分配隐藏：顺序编号、不透明、密封信封。盲法：单盲（结果评估者）。
每组有 17 名患者纳入统计分析。在两组中，实验组的犬齿回缩率在第一个月比对照组高出两倍，在第二个月高出 1.5 倍（p<0.001）。此外，两组实验组的犬齿回缩总持续时间比对照组缩短了约 25%（p≤0.001）。在两组中，实验组和对照组在支抗丧失和上颌犬齿旋转方面均无显著差异（p>0.05）。在所有评估时间内，两种无瓣技术之间在研究变量方面均无显著差异（p>0.05）。
超声骨刀切割和激光辅助无瓣皮质切开术似乎是加速犬齿回缩的有效治疗方法，在快速回缩过程中对支抗或犬齿旋转没有任何不良影响。
ClinicalTrials.gov（标识符：NCT02606331）。
