• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

儿童亚临床甲状腺功能减退症：它总是亚临床的吗？

Subclinical hypothyroidism in children: is it always subclinical?

机构信息

UOC Pediatria, Department of Human Pathology of Adulthood and Childhood, University of Messina, via Consolare Valeria, 98125, Messina, Italy.

出版信息

Ital J Pediatr. 2018 Feb 17;44(1):25. doi: 10.1186/s13052-018-0462-4.

DOI:10.1186/s13052-018-0462-4
PMID:29454373
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5816505/
Abstract

Aim of this commentary is to report current knowledges on the main clinical and metabolic abnormalities which might be observed in children with longstanding and untreated subclinical hypothyroidism (SH) and to comment the most recent views about natural evolution of thyroid function in the cases with either idiopathic or Hashimoto's thyroiditis-related SH. On the basis of these preliminary remarks, the essential guidelines for an appropriate and tailored management of SH children are also proposed.

摘要

本评论旨在报告长期未经治疗的亚临床甲状腺功能减退症（SH）患儿可能出现的主要临床和代谢异常的现有知识，并对特发性或桥本甲状腺炎相关 SH 病例甲状腺功能的自然演变的最新观点进行评论。在此基础上，还提出了 SH 儿童适当和个体化管理的基本指南。

相似文献

1
Subclinical hypothyroidism in children: is it always subclinical?儿童亚临床甲状腺功能减退症：它总是亚临床的吗？
Ital J Pediatr. 2018 Feb 17;44(1):25. doi: 10.1186/s13052-018-0462-4.
2
Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children.儿童亚临床甲状腺功能减退症随时间演变的影响因素分析。
Ital J Pediatr. 2017 Jan 3;43(1):2. doi: 10.1186/s13052-016-0322-z.
3
Thyroid function test evolution in children with Hashimoto's thyroiditis is closely conditioned by the biochemical picture at diagnosis.桥本甲状腺炎患儿的甲状腺功能测试演变与诊断时的生化情况密切相关。
Ital J Pediatr. 2018 Feb 7;44(1):22. doi: 10.1186/s13052-018-0461-5.
4
Five-Year Prospective Evaluation of Thyroid Function Test Evolution in Children with Hashimoto's Thyroiditis Presenting with Either Euthyroidism or Subclinical Hypothyroidism.对表现为甲状腺功能正常或亚临床甲状腺功能减退的桥本甲状腺炎患儿甲状腺功能检查变化的五年前瞻性评估。
Thyroid. 2016 Oct;26(10):1450-1456. doi: 10.1089/thy.2016.0080. Epub 2016 Sep 13.
5
The natural course of Hashimoto's thyroiditis in children and adolescents.儿童及青少年桥本甲状腺炎的自然病程。
J Pediatr Endocrinol Metab. 2014 Sep;27(9-10):807-12. doi: 10.1515/jpem-2013-0373.
6
Evaluation of thyroid gland function in children with obstructive apnea hypopnea syndrome.评估阻塞性睡眠呼吸暂停低通气综合征患儿的甲状腺功能。
Int J Immunopathol Pharmacol. 2011 Apr-Jun;24(2):377-86. doi: 10.1177/039463201102400211.
7
Selenium and its relationship with selenoprotein P and glutathione peroxidase in children and adolescents with Hashimoto's thyroiditis and hypothyroidism.硒及其与桥本甲状腺炎和甲状腺功能减退症儿童及青少年中硒蛋白P和谷胱甘肽过氧化物酶的关系。
J Trace Elem Med Biol. 2016 Mar;34:10-4. doi: 10.1016/j.jtemb.2015.10.003. Epub 2015 Nov 18.
8
Underlying Hashimoto's thyroiditis negatively affects the evolution of subclinical hypothyroidism in children irrespective of other concomitant risk factors.潜在的桥本甲状腺炎会对儿童亚临床甲状腺功能减退的进展产生负面影响，无论是否存在其他伴随的风险因素。
Thyroid. 2015 Feb;25(2):183-7. doi: 10.1089/thy.2014.0235. Epub 2014 Dec 2.
9
Five-year prospective evaluation of thyroid function in girls with subclinical mild hypothyroidism of different etiology.不同病因亚临床轻度甲状腺功能减退症女孩的 5 年甲状腺功能前瞻性评估。
Eur J Endocrinol. 2015 Dec;173(6):801-8. doi: 10.1530/EJE-15-0484. Epub 2015 Sep 15.
10
In children with Hashimoto's thyroiditis the evolution over time of thyroid status may differ according to the different presentation patterns.在患有桥本甲状腺炎的儿童中，甲状腺状态随时间的演变可能因不同的表现模式而有所不同。
Acta Biomed. 2015 Sep 14;86(2):137-41.

引用本文的文献

1
Hypothyroidism among children and adolescents with nephrotic syndrome in Mulago National Referral Hospital, Kampala, Uganda; a cross-sectional study.乌干达坎帕拉穆拉戈国家转诊医院肾病综合征儿童及青少年甲状腺功能减退症的横断面研究
BMC Pediatr. 2024 Feb 19;24(1):132. doi: 10.1186/s12887-024-04610-8.
2
Prevalence and factors associated with hypothyroidism in children with sickle cell anemia aged 6 months - 17 years attending the Sickle Cell Clinic, Mulago Hospital, Uganda; a cross-sectional study.乌干达穆拉戈医院镰状细胞贫血科就诊的 6 个月至 17 岁儿童中甲状腺功能减退症的患病率及其相关因素：一项横断面研究。
BMC Endocr Disord. 2023 Mar 13;23(1):60. doi: 10.1186/s12902-023-01317-2.
3
Subclinical Hypothyroidism in Pediatric Age: How Important Is Autoimmunity?儿童期亚临床甲状腺功能减退症：自身免疫有多重要？
Cureus. 2022 Aug 28;14(8):e28507. doi: 10.7759/cureus.28507. eCollection 2022 Aug.
4
The Role of Iodine for Thyroid Function in Lactating Women and Infants.哺乳期妇女和婴儿的甲状腺功能的碘作用。
Endocr Rev. 2022 May 12;43(3):469-506. doi: 10.1210/endrev/bnab029.
5
Hashimoto Thyroiditis and Dyslipidemia in Childhood: A Review.儿童桥本甲状腺炎与血脂异常：综述
Front Endocrinol (Lausanne). 2019 Dec 10;10:868. doi: 10.3389/fendo.2019.00868. eCollection 2019.
6
Report on advances for pediatricians in 2018: allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroenterology, infectious diseases, neonatology, nutrition, respiratory tract disorders and surgery.2018 年儿科医师进展报告：过敏、心脏病学、重症监护、内分泌学、遗传性代谢疾病、胃肠病学、传染病、新生儿学、营养、呼吸道疾病和外科学。
Ital J Pediatr. 2019 Oct 16;45(1):126. doi: 10.1186/s13052-019-0727-6.
7
Evaluation of cardiovascular risk by growth-differentiation factor-15 and tissue Doppler imaging in children with subclinical hypothyroidism.应用生长分化因子 15 和组织多普勒成像评估亚临床甲状腺功能减退症患儿的心血管风险。
Endocrine. 2019 Sep;65(3):601-607. doi: 10.1007/s12020-019-01933-w. Epub 2019 Apr 19.
8
Subclinical Hypothyroidism in Children: When a Replacement Hormonal Treatment Might Be Advisable.儿童亚临床甲状腺功能减退症：何时可能适合进行替代激素治疗。
Front Endocrinol (Lausanne). 2019 Feb 25;10:109. doi: 10.3389/fendo.2019.00109. eCollection 2019.

本文引用的文献

1
Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children.儿童亚临床甲状腺功能减退症随时间演变的影响因素分析。
Ital J Pediatr. 2017 Jan 3;43(1):2. doi: 10.1186/s13052-016-0322-z.
2
Five-Year Prospective Evaluation of Thyroid Function Test Evolution in Children with Hashimoto's Thyroiditis Presenting with Either Euthyroidism or Subclinical Hypothyroidism.对表现为甲状腺功能正常或亚临床甲状腺功能减退的桥本甲状腺炎患儿甲状腺功能检查变化的五年前瞻性评估。
Thyroid. 2016 Oct;26(10):1450-1456. doi: 10.1089/thy.2016.0080. Epub 2016 Sep 13.
3
Subclinical hypothyroidism in childhood - current knowledge and open issues.儿童亚临床甲状腺功能减退症 - 现有知识和未解决的问题。
Nat Rev Endocrinol. 2016 Dec;12(12):734-746. doi: 10.1038/nrendo.2016.100. Epub 2016 Jul 1.
4
Effects of L-thyroxine treatment on early markers of atherosclerotic disease in children with subclinical hypothyroidism.左甲状腺素治疗对亚临床甲状腺功能减退症儿童动脉粥样硬化疾病早期标志物的影响。
Eur J Endocrinol. 2016 Jul;175(1):11-9. doi: 10.1530/EJE-15-0833. Epub 2016 Apr 11.
5
Five-year prospective evaluation of thyroid function in girls with subclinical mild hypothyroidism of different etiology.不同病因亚临床轻度甲状腺功能减退症女孩的 5 年甲状腺功能前瞻性评估。
Eur J Endocrinol. 2015 Dec;173(6):801-8. doi: 10.1530/EJE-15-0484. Epub 2015 Sep 15.
6
Interpreting Minor Variations in Thyroid Function or Echostructure: Treating Patients, Not Numbers or Images.解读甲状腺功能或回声结构的微小变化：治疗患者，而非数字或图像。
Pediatr Clin North Am. 2015 Aug;62(4):929-42. doi: 10.1016/j.pcl.2015.04.008. Epub 2015 Jun 24.
7
Peculiarities of autoimmune thyroid diseases in children with Turner or Down syndrome: an overview.特纳综合征或唐氏综合征患儿自身免疫性甲状腺疾病的特点：综述
Ital J Pediatr. 2015 May 15;41:39. doi: 10.1186/s13052-015-0146-2.
8
Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis.亚临床甲状腺功能减退与中风事件及致命性中风风险：个体参与者数据分析
J Clin Endocrinol Metab. 2015 Jun;100(6):2181-91. doi: 10.1210/jc.2015-1438. Epub 2015 Apr 9.
9
Underlying Hashimoto's thyroiditis negatively affects the evolution of subclinical hypothyroidism in children irrespective of other concomitant risk factors.潜在的桥本甲状腺炎会对儿童亚临床甲状腺功能减退的进展产生负面影响，无论是否存在其他伴随的风险因素。
Thyroid. 2015 Feb;25(2):183-7. doi: 10.1089/thy.2014.0235. Epub 2014 Dec 2.
10
Serum thyrotropin is positively correlated with the metabolic syndrome components of obesity and dyslipidemia in chinese adolescents.血清促甲状腺激素与中国青少年肥胖和血脂异常的代谢综合征成分呈正相关。
Int J Endocrinol. 2014;2014:289503. doi: 10.1155/2014/289503. Epub 2014 Aug 21.