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腹式子宫肌瘤剔除术是否会导致粘连?

Are synechiae a complication of laparotomic myomectomy?

机构信息

Service de Gynécologie Obstétrique, Hôpital Bicêtre, GHU Sud, AP-HP, F-94276, Le Kremlin Bicêtre, France; Inserm, Centre of research in Epidemiology and population health (CESP), U1018, F-94276, Le Kremlin Bicêtre, France; Faculty of medicine, Univ Paris Sud, F-94276, Le Kremlin Bicêtre, France.

Service de Gynécologie Obstétrique, Hôpital Bicêtre, GHU Sud, AP-HP, F-94276, Le Kremlin Bicêtre, France.

出版信息

Reprod Biomed Online. 2018 Apr;36(4):450-454. doi: 10.1016/j.rbmo.2018.01.010. Epub 2018 Feb 2.

Abstract

Laparotomic myomectomy is often the only realistic solution for symptomatic women with multiple or large myomas who wish to retain their fertility. The aim of this study was to document the rate of uterine synechiae and their associated risk factors after laparotomic myomectomy. This prospective observational study took place in a teaching hospital from May 2009 to June 2014. It included all women aged 18-45 years who had laparotomic myomectomies (without diagnostic hysteroscopy at the time of surgery) for myomas and a postoperative diagnostic office hysteroscopy 6-8 weeks later. The study included 98 women with a laparotomic myomectomy and a postoperative hysteroscopic follow-up. Women with a laparotomic myomectomy for a subserosal myoma were excluded. The intrauterine adhesion rate after laparotomic myomectomy was 25.51% (25/98); 44% (11/25) of them were complex intrauterine adhesions. Opening the uterine cavity was a major risk factor for these complex adhesions, with an OR of 6.42 (95% CI 1.27 to 32.52). Office hysteroscopy could be carried out after surgery in such cases.

摘要

剖腹子宫肌瘤剔除术通常是有生育要求的多发性或大型子宫肌瘤有症状妇女的唯一现实解决方案。本研究旨在记录剖腹子宫肌瘤剔除术后子宫粘连的发生率及其相关危险因素。这是一项前瞻性观察研究,于 2009 年 5 月至 2014 年 6 月在一所教学医院进行。纳入标准为年龄 18-45 岁、因子宫肌瘤行剖腹子宫肌瘤剔除术(手术时无诊断性宫腔镜检查)且术后 6-8 周行宫腔镜诊断性随访的所有患者。本研究共纳入 98 例行剖腹子宫肌瘤剔除术且术后行宫腔镜随访的患者。剔除因浆膜下子宫肌瘤而行剖腹子宫肌瘤剔除术的患者。剖腹子宫肌瘤剔除术后宫腔粘连发生率为 25.51%(25/98);其中 44%(11/25)为复杂性宫腔粘连。子宫腔的开放是导致这些复杂性粘连的主要危险因素,OR 值为 6.42(95%CI 1.27 至 32.52)。在这种情况下,术后可以进行宫腔镜检查。

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