波兰多发性硬化症的流行情况。

Prevalence of multiple sclerosis in Poland.

机构信息

Department of Neurology, Medical University of Bialystok, Bialystok, Poland.

Department of Neurology, Specialist Hospital, Konskie, Poland.

出版信息

Mult Scler Relat Disord. 2018 Apr;21:51-55. doi: 10.1016/j.msard.2018.02.016. Epub 2018 Feb 12.

DOI:10.1016/j.msard.2018.02.016

PMID:29455075

Abstract

OBJECTIVE

The prevalence of multiple sclerosis (MS)was previously unknown in Poland. The aim of this study was to determine the prevalence of MS in Poland.

METHODS

MS prevalence was determined on the basis of data from the Swietokrzyskie (central Poland) and Podlaskie (northeastern Poland) Voivodeships. The area population on the prevalence study day (December 31, 2013) was 1,268,239 (649,007 women; 619,232 men) in central and 1,195,625 (612,979 women; 582,646 men) in northeastern Poland.

RESULTS

The overall crude prevalence rate of confirmed MS patients was 109.1/100,000 (95% confidence interval[CI]103.5-115.0) in the Swietokrzyskie and 108.7/100,000 (95% CI 103.0-114.7) in the Podlaskie Voivodeships. A significantly higher prevalence was recorded in females (149.8/100,000, 95% CI 140.6-159.3 vs. 142.4/100,000, 95% CI 133.3-152.0) than in males (66.5/100,000, 95% CI 60.4-73.1 vs.57.8/100,000, 95% CI 52.0-64.2)(p < 0.001). Age-adjusted rates for the Polish Standard Population were the same in both regions (110.3/100,000 (95% CI 104.6-116.1) vs.110.9/100,000 (95% CI 105.1-117.1)) and for the European Standard Population did not different statistically between both voivodeships (103.9/100,000 (95% CI 98.6-109.5) vs.108.5/100,000 (95% CI 102.7-114.5)).

CONCLUSION

This is the first data that obtained the level of MS prevalence in Poland and confirmed that Poland is a high-risk area for multiple sclerosis.

摘要

目的

多发性硬化症（MS）在波兰的流行情况此前尚不清楚。本研究旨在确定波兰的 MS 流行率。

方法

基于来自圣十字省（波兰中部）和波德拉谢省（波兰东北部）的数据确定 MS 流行率。在流行研究日（2013 年 12 月 31 日），该地区的人口为 1,268,239 人（女性 649,007 人；男性 619,232 人），占波兰中部的 1,195,625 人（女性 612,979 人；男性 582,646 人）。

结果

圣十字省确诊 MS 患者的总粗患病率为 109.1/100,000（95%置信区间[CI]103.5-115.0），波德拉谢省为 108.7/100,000（95%CI 103.0-114.7）。女性的患病率明显高于男性（女性为 149.8/100,000，95%CI 140.6-159.3 与男性 142.4/100,000，95%CI 133.3-152.0）（p<0.001）。调整年龄后的波兰标准人口发病率在两个地区相同（110.3/100,000（95%CI 104.6-116.1）与 110.9/100,000（95%CI 105.1-117.1）），欧洲标准人口发病率在两个省之间统计学上没有差异（103.9/100,000（95%CI 98.6-109.5）与 108.5/100,000（95%CI 102.7-114.5））。