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评估比利时癌症患者长期工作残疾的相关因素:一项基于人群的队列研究,采用竞争风险分析,随访7年。

Assessing factors associated with long-term work disability after cancer in Belgium: a population-based cohort study using competing risks analysis with a 7-year follow-up.

作者信息

Kiasuwa Mbengi Régine Levo, Nicolaie Alina Mioara, Goetghebeur Els, Otter Renee, Mortelmans Katrien, Missinnne Sarah, Arbyn Marc, Bouland Catherine, de Brouwer Christophe

机构信息

Belgian Cancer Centre, Scientific Insitute of Public Health, Brussels, Belgium.

Research Centre for Environmental and Occupational Health, Brussels School of Public Health, Université Libre de Bruxelles (ESP-ULB), Brussels, Belgium.

出版信息

BMJ Open. 2018 Feb 17;8(2):e014094. doi: 10.1136/bmjopen-2016-014094.

Abstract

OBJECTIVES

The number of workers with cancer has dramatically increasing worldwide. One of the main priorities is to preserve their quality of life and the sustainability of social security systems. We have carried out this study to assess factors associated with the ability to work after cancer. Such insight should help with the planning of rehabilitation needs and tailored programmes.

PARTICIPANTS

We conducted this register-based cohort study using individual data from the Belgian Disability Insurance. Data on 15 543 socially insured Belgian people who entered into the long-term work disability between 2007 and 2011 due to cancer were used.

PRIMARY AND SECONDARY OUTCOME MEASURES

We estimated the duration of work disability using Kaplan-Meier and the cause-specific cumulative incidence of ability to work stratified by age, gender, occupational class and year of entering the work disability system for 11 cancer sites using the Fine and Gray model allowing for competing risks.

RESULTS

The overall median time of work disability was 1.59 years (95% CI 1.52 to 1.66), ranging from 0.75 to 4.98 years. By the end of follow-up, more than one-third of the disabled cancer survivors were able to work (35%). While a large proportion of the women were able to work at the end of follow-up, the men who were able to work could do so sooner. Being women, white collar, young and having haematological, male genital or breast cancers were factors with the bestlikelihood to be able to return to work.

CONCLUSION

Good prognostic factors for the ability to work were youth, woman, white collar and having breast, male genital or haematological cancers. Reviewing our results together with the cancer incidence predictions up to 2025 offers a high value for social security and rehabilitation planning and for ascertaining patients' perspectives.

摘要

目的

全球患癌工人数量急剧增加。其中一个主要优先事项是维护他们的生活质量以及社会保障系统的可持续性。我们开展这项研究以评估与癌症后工作能力相关的因素。此类见解应有助于康复需求规划和量身定制方案。

参与者

我们利用比利时残疾保险的个人数据进行了这项基于登记的队列研究。使用了2007年至2011年期间因癌症进入长期工作残疾状态的15543名参加社会保险的比利时人的数据。

主要和次要结局指标

我们使用Kaplan-Meier法估计工作残疾持续时间,并使用允许存在竞争风险的Fine和Gray模型,按年龄、性别、职业类别以及进入工作残疾系统的年份,对11种癌症部位的工作能力特定病因累积发病率进行分层分析。

结果

工作残疾的总体中位时间为1.59年(95%置信区间1.52至1.66),范围为0.75至4.98年。到随访结束时,超过三分之一的残疾癌症幸存者能够工作(35%)。虽然很大一部分女性在随访结束时能够工作,但能够工作的男性恢复工作的时间更早。女性、白领、年轻以及患有血液系统、男性生殖系统或乳腺癌是最有可能恢复工作的因素。

结论

工作能力的良好预后因素为年轻、女性、白领以及患有乳腺、男性生殖系统或血液系统癌症。结合直至2025年的癌症发病率预测来审视我们的结果,对社会保障和康复规划以及确定患者观点具有很高价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16cc/5855469/e8d3a93841b0/bmjopen-2016-014094f01.jpg

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