Medrano G A, de Micheli A, Osornio Vargas A
Arch Inst Cardiol Mex. 1986 Jul-Aug;56(4):283-8.
Electrical changes produced by an experimental left atrial infarction were studied in 15 mongrel dogs, anesthetized by sodium pentobarbital intravenously and submitted to intratracheal intubation, medical sternotomy and heart exposition without open the pericardial sac. 5 to 8 ml of alcohol 96 degrees were infiltrated into left atrial myocardium by means of a thin needle introduced superficially and parallel to the visceral pericardium. Left atrial damage reduces the electromotive, forces corresponding to the anterolateral portions of the left atrium giving rise to QS or QR slurred P waves with very delayed activation when left portion of interatrial band was damaged. Surface ECG records bimodal wide P waves with or without a qp wave in V2-V4 leads, associated to STa elevation in lead a VL and higher leads in the fourth and third left intercostal spaces at the vertical line of V4. QTac interval is more prolonged in right than in left registries as it was observed in right atrial damage, which implies a more earlier repolarization of left atrium. These data are useful for diagnosis of infarction or myocarditis.
对15只杂种犬进行了实验性左心房梗死产生的电变化研究，这些犬经静脉注射戊巴比妥钠麻醉，并进行气管插管、正中胸骨切开术和心脏暴露，但不打开心包囊。通过一根与脏层心包平行浅插的细针，将5至8毫升96度酒精注入左心房心肌。当房间隔带左侧受损时，左心房损伤会降低与左心房前外侧部分相对应的电动势，导致QS或QR型模糊P波，激活非常延迟。体表心电图在V2-V4导联记录到双峰宽P波，有或无qp波，与aVL导联及V4垂直线上左第4和第3肋间更高导联的STa抬高相关。QTac间期在右侧记录中比左侧记录中延长得更多，正如在右心房损伤中观察到的那样，这意味着左心房复极更早。这些数据对梗死或心肌炎的诊断有用。
